Genetics II - Population Genetics Flashcards
Define allele
A single copy of a gene
Define genotype
The pair of alleles in an individual
Define polygenic traits?
Characteristics influenced by more than one gene
Define gene interaction
A single trait controlled by 2 or more genes
- each of which has multiple alleles within a population of individuals.
Define monomorphic gene
A gene which exists as a single allele in a population
- so all individuals are automatically homozygous for it as the 2 copies are the same.
Define polymorphic gene
A gene that has 2 or more allelic variants within a population
- homozygous: both copies same
- heterozygous: copies differ
What is population genetics?
Study of genes and genotypes in a population
Define gene pool
All of the alleles for every gene in a given population
What are single nucleotide polymorphisms (SNPs)?
Smallest type of genetic change in a gene
How do you calculate allele frequency?
(no. of copies of a specific allele in a population) / (total number if all alleles for that gene in a population)
How do you calculate genotype frequency?
(no. of individuals with a particular genotype in a population) / (total number of individuals in a population)
What is the Hardy-Weinberg equation?
Sums all genotype frequencies for a given gene in a population.
What is the mathematical Hardy-Weinberg equation?
p^2 + 2pq + q^2 = 1
What does the Hardy-Weinberg law state?
That allele and genotype frequencies in population will remain constant from generation to generation in the absense of other evolutionary influences.
What are the conditions for Hardy-Weinberg Equilibrium?
- no new mutations occur
- no natural selection occurs
- pop so large that allele frequencies do not change due to random sampling error
- no migration changes between diff pops
- random mating occurs