Genetics & Cancer Flashcards

1
Q

Gene

A

A gene is the basic physical and functional unit of heredity. Genes, which are made up of DNA, act as instructions to make molecules called proteins

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2
Q

Allele

A

Different versions of the same gene.

Allele X or allele x

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3
Q

Chromosome

A

Thread-like structures that make up DNA found within the nucleus of a molecule.

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4
Q

Homologous Chromosome

A

Code for the same gene

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5
Q

Genotype

A

Genes present in an individual.

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6
Q

Heterozygous Genotype

A

Exact version of the alleles I have. Bb (different allele).

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7
Q

Homozygous Genotype

A

Version of the allele I have. bb (same allele)

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8
Q

Genotype

A

Exact genes you have Bb

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9
Q

Phenotype

A

Physical expression of a particular trait.

Bb –> the dominant gene B is expressed

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10
Q

Autosomes

A

One chromosome pair.

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11
Q

Zygote

A

Formed by the combination of 23 pairs of chromosomes. One set coming from each parent.

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12
Q

Meiosis

A

Cellular division process in which gametes are produced which contain half the chromosomes of the parent cell.

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13
Q

Mitosis

A

Type of cell division in which cells are produced with exactly the same kind and number of chromosomes as the parent cell.

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14
Q

Genetic Mutations

A

Occur as a result of:

  • Errors in the copying process during replication of DNA cells
  • environmental factors (radiation/chemicals)

Can occur in sex cells which are passed on to future generations.

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15
Q

Mutation

A

An event that changes the genetic structure or sequence of a cell.

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16
Q

Carcinogenesis

A

Mutations that occur over many years causing the growth and division of cells to be uncontrolled resulting in development of cancer from normal tissue.

17
Q

Carcinogens

A

Agents which predispose timor development.

May be chemical, physical (radiation) or viral (HPV –> cervical cancer)

18
Q

Carcinoma

A

Malignant tumor of epithelial tissue.

19
Q

Adeoma

A

Benign timor of epithelial tissue.