Genetics, Biodiversity and Classification Flashcards
Species
- similar DNA sequence
- same ecological niche
- can breed to produce fertile offspring
Genetic diversity
Total number of different alleles in a population
Genetic mutation
Random change in base sequence of DNA
Causes of genetic mutation
- spontaneously during DNA replication
- high energy radiation / ionising radiation
- carcinogens
Describe impact of deletion of nucleotide from original DNA sequence
Alters reading frame of gene downstream of mutation - potential to change all triplets so affects formation of multiple amino acids
Chromosome mutation
Change to structure or number of chromosomes
Non-disjunction
Failure of homologous pairs/ sister chromatids to separate during meiosis so cells have fewer or more chromosomes after fertilisation
Polyploidy
More than one complete set of chromosomes
Homologous Pair
Pair of chromosomes - maternal and paternal
Same gene loci
Importance of meiosis
- number of chromosomes halved so diploid number is restored at fertilisation
- genetic variation from independent segregation and cross over
Cross over
- homologous pairs come together in a bivalent and their chromatids becomes twisted forming a chiasma
- equivalent LENGTHS OF non sister CHROMATIDS exchanged
- new combinations of alleles
Independent Segregation
- formation of random combinations of maternal and paternal chromosomes in a homologous pair during metaphase I (meiosis)
- chromosomes of each homologous pair sort into gametes independently of another pair
Meiosis - Prophase
DNA condenses so chromosomes are visible
Nuclear envelope breaks down
Spindle fibres form
(1) cross over occurs
Meiosis - Metaphase
Spindle fibres attach to chromosomes and they align at equator
(1) in homologous pairs - independent segregation/crossover
(2) random alignment of sister chromatids
Meiosis - Anaphase
Spindle fibres contract and shorten
(1) one chromosome from each homologous pair migrates to opposite pole
(2) chromatids pulled apart
Meiosis - Telophase
Nuclear envelope reforms and chromosomes unravel
Importance of genetic diversity
- species more likely to survive environmental change
- greater probability an individual posses allele which allows it to survive
What is evolution and what factors cause it to take place
Change in allele frequency over time
- genetic variation
- selection pressures
Natural Selection
- genetic MUTATIONS create different alleles
- SELECTION PRESSURE
- certain alleles are advantageous
- individuals with this allele more likely to survive and reproduce so have selective advantage
- frequency of allele increases
Evidence for evolution
- genetic code and ATP is universal
- all proteins formed from same 20 amino acids
Reasons for classifying organisms
- easier to study
- understand evolutionary relationships
- keep track of changes
Artificial classification and its benefits/drawbacks
Grouping organisms based on FREQUENCY of similar observable characteristics (phenotype)
- stable classification
- simplified method of grouping individuals
- individually are usually not phylogenetically related since phenotype affected by environment
- provides limited information (cannot sort into species etc.)
Phylogenetic Classification
Grouping organisms based on evolutionary relationships where shared features are derived from a common ancestor
Evidence of phylogenetic classification
- common ancestors
- proportion of similar DNA since mutations occur over time
- comparison of amino acid sequences in cytochrome C (found in all eukaryotes)
- immunological comparisons of proteins using antibodies