Genetics and Aging Flashcards
1
Q
Mutation in this gene will extend lifespan in C. Elegans
A
Daf-2 Gene
2
Q
Human Non-Coding Repeat Sequence
A
TTAGGG
3
Q
Where do Telomerases add repeats?
A
3’ ends of telomeres
4
Q
Famous tumor-suppressor protein
A
P53
5
Q
Function: Proto-oncogenes
What could happen when they mutate?
A
Responsible for promoting cell growth.
Mutated: Become oncogenes that stimulate tumor formation/growth
6
Q
Genes Associated with Type 2 Diabetes (2)
A
CAPN10: Calpain 10
HNF4A: Hepatocyte Nuclear Factor 4
7
Q
UV Radiation usually links what?
A
Thymine
8
Q
What dimers are formed from UV radiation?
A
Cyclobutane Pyrimidine Dimers