Genetics Flashcards
term for: individual traits are inherited separately from each other
Independent Segregation (Mendel)
<p>term for: genes for different traits are inherited separately from each other</p>
<p>Independent Assortment (Mendel)</p>
Hardy-Weinberg principle (2 equations, definition for each unknown)
p + q = 1 p^2 + 2pq + q^2= 1
p = gene frequency of dominant allele q = gene frequency of recessive allele
In humans, there are ____ pairs of autosomes and ___ pairs of sex chromosomes
22 pairs of autosomes and 1 pair of sex chromosomes
a segment of DNA that encodes a particular protein
a gene
a genetically determined characteristic or condition
a trait
alternative forms of a gene
alleles
Two blood group systems encoded by X-borne genes
Xg system (XG gene) and Kx system (XK gene)
Mutations or deletions in ____ gene result in McLeod phenotype red cells that lack ___ antigens and have reduced expression of ___ antigens
XK gene, lack Kx antigens, reduced Kell antigens
The only blood group system gene subject to X-chromosome inactivation
Kx. Female carriers can have a dual population of Kx+ and Kx- cells
The H and Se genes are located on chromosome ___
19
ABO genes are located on chromosome ___
9q34
The H gene elicits the production of an enzyme called ____________ which transfers the sugar _____ to an oligosaccharide chain on the terminal galactose of type 2 chains
α-2-L-fucosyltransferase; L-fucose
H gene’s glycosyltransferase:
α-2-L-fucosyltransferase
H gene’s immunodominant sugar:
L-fucose
“A” gene’s glycosyltransferase:
α-3-N-acetylgalactosaminyltransferase
“A” gene’s immunodominant sugar:
N-acetyl-D-galactosamine (GalNAc)
“B” gene’s glycosyltransferae:
α-3-D-galactosyltransferase
“B” gene’s immunodominant sugar:
D-galactose
% of population who are secretors (Sese or SeSe)
80%
