Genetic Mapping/Positional Cloning

Question 1

Genetic Marker

Answer 1

Mutation where the size and position on both genetic and physical maps are known. Must be genetically inert (no phenotype).

Question 2

Genetic Linkage Mapping

Answer 2

Measured in recombination frequency (centimorgans (cM), alternatively known as a map unit (m.u.))
On a scale from -25 to +25 cM. This is because 50 is the highest possible percentage of recombination frequency.

Question 3

Physical Mapping

Answer 3

Measured in base pairs.

On a scale from Base “1” to Base “n”.

Question 4

SNPs

Answer 4

Single Nucleotide Polymorphisms. Can be detected by sequencing.

Question 5

Three Factor Mapping

Answer 5

Uses 2 mutations as genetic markers.

Question 6

Quantitative Trait Mapping

Answer 6

Map using a QTL (Quantitative trait locus)