Genetic Mapping Flashcards
1
Q
What is a 2-point analysis?
A
1 locus is the disease locus and the other point is a marker
2
Q
Informative meiosis
A
A meiosis is informative when recombinants can be determined
3
Q
What is the main point of genetic mapping?
A
That one of the alleles of that marker will always co-segregate with the disease because it is on the same chromosome that is inherited by affected individuals
4
Q
Why will the allele be different in different pedigrees?
A
because the mutation may not be the same on a molecular level
5
Q
Identical by descent allele
A
Same allele because the same chromosome is inherited
6
Q
identical by state
A
Same allele on the same marker so not necessarily reflecting the same chromosome
