Genetic Information, Varietion And Relationships Between Organisms Flashcards
Compare eukaryotic and prokaryotic DNA cells
- both made up of dna nucleotides containing deoxyribose, phosphate group and a nitrogenous based
- nucleotides joined together by phosphodiesterbhonde to make a polymer chain
- eukaryotic cells are longer where prokaryotic cells are shorter
- eukaryotic cells are linear where prokaryotic are circular
- eukaryotic cells are associated with histones where prokaryotic cells aren’t
What is the name for DNA wrapped around histones?
Nucleosomes
Similarities between dna in mitochondria/ chloroplast and prokaryotic cells
- short
- circular
- not associated with a protein
What is a gene
- a base sequence of DNA that codes for the amino acid sequence of a polypeptide and a functional RNA
What is a locus
- exact position of a gene on a chromosome
What is a triplet
- a sequence of 3 DNA bases that code for a specific amino acid
What are the 3 features of the genetic code?
- degenerate, universal and non overlapping
What is meant by degenerate?
- different base sequences code for the same amino acid
What is meant by universal?
- same base triplet code for the amino acid
What is meant by non overlapping?
- each base is only read once and only part of one triplet
Why is degeneracy an advantage?
- if there is a mutation , even if the base triplet is different it may still code for the same amino acid
Why is non overlapping an advantage?
- if there is a mutation, it will only affect 1 codon minimising the harm done
What is an intron
- sections of DNA that don’t code for polypeptide found in eukaryotic DNA but not prokaryotic
What are exons?
- sequences of DNA that code for amino acids
What is a codon?
- 3 bases on mRNA and jay for for w specific amino acid
What is a start codon?
- three bases at the start of every gene that initiate translation
What is a stop codon?
- three bases at the end of every gene that cause ribosomes to detach and stop translation
What is meant by genome
- complete set of genes in a cell
What is meant by a proteome?
- full range of proteins a cell can produce
What is mRNA?
- short, single polynucleotide strand found in the cytoplasm and nucleus. Has codons complimentary to anticodons on tRNA
What is tRNA
- single polynucleotide strand folded into a clover leaf shape joined together by H bonds. Has an amino acid binding site and a binding site where it’s anticodons bind with their complimentary codons on mRNA
Describe the process of transcription
- DNA Helicase breaks H bonds between complimentary base pairs and unzips double strand
- Only one DNA strand acts as a template for mRNA production
- RNA nucleotides attracted to exposed bases
- RNA polymerase joins nucleotides together
- Pre mRNA is spliced to remove introns
Explain the process of Translation
- Ribosomes attached to mRNA
- Ribosomes move to start codon
- tRNA molecule carries specific amino acid and the anticodon on tRNA pairs with complimentary codon on mRNA
- Ribosome moves along to the next codon and can only fit 2 tRNAS
- Amino acids join to form peptide bonds
What is a gene mutation?
A change in the base sequence of DNA, randomly occurs during DNA replication