Genetic information, variation and relationships between organisms-Genetic diversity can arise as a result of mutation or during meiosis Flashcards
What is a Gene?
a section of DNA that codes for a protein
made out of intron and exon
intron = non-coding DNA (function e.g. turns gene on or off)
exon = coding DNA (codes for protein)
How does a Gene/Exon code for a Protein?
made out of a sequence of bases
each 3 bases code for 1 amino acid (called triplet code)
therefore,
sequence of bases
determines sequence of triplet codes
which determine the sequence of AAs
= polypeptide chain/primary structure (folds to secondary, then to tertiary/quaternary)
Properties of triplet code?
degenerate = each AA has more than one triplet code
non-overlapping = each base is read only once
stop codes = occur at end of sequence – do not code for an AA
How does a mutation lead to a non-functional enzyme?
change in base sequence change in sequence of triplet codes change in sequence of AAs change in primary structure change in tertiary structure change in active site shape can no longer form enzyme-substrate complex
How is a protein assembled?
by transcription and translation
transcription = production of a single stranded complementary copy of a gene (called mRNA)
translation = use sequence of codons on mRNA to assemble protein (tRNA brings in AAs)