Genetic explanation Flashcards
Genetic explanation
-Schizophrenia is inherited from faulty genes which are passed on from individuals to families causing the disorder, it is a polygenetic disorder, multiple genes such as the PCM1 gene have been implicated in the onset of the disorder. Genetic studies suggest high concordance rate for MZ twins who share identical DNA
Gottesman
75-91% concordance rate of MZ twins both having schizophrenia-genetic component
Goury
Used gene mapping to identify the PCM1 gene as creating a disposition to schizophrenia
-Limitations
-Concordance rates aren’t 100%-external factors play a role in triggering the disposition, cannot solely explain schizophrenia
-Reductionist, overlooks the role of other factors like dopamine
-Reductionist, overlooks the role of environmental factors-better explained by a diathesis stress model