Genes relacionados ao câncer Flashcards

1
Q

Genes ligados à oncogênese (5)

A

SRC E RAS,BRAF,NRAS E KIT

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1
Q

Genes supressores de tumor(2)

A

Retinoblastoma (RB) e TP53

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2
Q

Genes reparadores de DNA (4)

A

BRCA-1 E BRCA-2, família UVDR e família MMR

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3
Q

Genes envolvidos na Queratose Actínica (2)

A

Alteração no gene TP53 e deleções no gene p16(gene supressor tumoral)

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4
Q

Genes envolvidos no CBC (4)

A

Sonic Hedgehog(SHH)

P53

PTCH

SMO(Smoothened

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5
Q

Genes relacionados ao melanoma

A

Mutações no CDKN2A(Principal)

CDK4

MCJR

BRAF(Melanomas extensivos superficias),NRAS(melanomas nodulares)KIT

PTEN

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