Genes in Populations - week 3 Flashcards

1
Q

what is the role of the animal breeder

A

to change populations, not individuals

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2
Q

what is a gene frequency/ allelic frequency

A

the relative frequency of a particular allele in a population

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3
Q

what is gene frequency/ allelic frequency a measure of

A

how common a particular allele is in a population

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4
Q

what does the relative frequency range from

A

0-1

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5
Q

what is the frequency if the allele frequency does not exist in a population

A

zero 0

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6
Q

what is the frequency if it is the only allele in the population

A

one 1

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7
Q

what is the frequency if it comprises 47% of the genes at locus in a population

A

the frequency is 0.47

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8
Q

what does p represent

A

frequency of the dominant allele

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9
Q

what does q represent

A

frequency of the recessive allelle

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10
Q

what does p+q always =

A

1

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11
Q

what is genotypic frequency

A

is the relative frequency of a one - locus genotype in a population

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12
Q

what does P represent

A

homozygous dominant genotypic frequency

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13
Q

what does H represent

A

heterozygous genotypic frequency

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14
Q

what does Q represent

A

homozygous recessive genotypic frequency

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15
Q

what does P+Q+H=

A

1

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16
Q

what is selection?

A

selection determines which animals breed

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17
Q

what is the effect of selection from a population genetic viewpoint

A

increase the frequency of favourable alleles

18
Q

what is the result of selection

A

the next generations should have better breeding values (set of genes)

19
Q

who invented Hardy weinberg equilibrium 1908

A

George Hardy - british mathematicain
Wilhelm weinbery - german physician

20
Q

what does the Hardy-Weinberg Equilibrium allow us to predict

A

the offspring genotype frequency using the parental genotype frequency

21
Q

what is the basic law of mendelian genetics

A

law of segregation

22
Q

what is the basic law of population genetics

A

hardy-Weinberg law

23
Q

(p+q)^2

A

1^2

p^2 +2pq+q^2=1
ratio: 1:2:1

24
Q

are domestic population in equilibrium

A

NO

25
Q

definition of equilibrium

A

that frequencies do not change between generations

26
Q

list 4 ways to change gene frequencies

A
  1. random genetic drift
  2. mutation
  3. migration
  4. selection - of most interest to animal breeders
27
Q

Effect of inbreeding on gene breeding

A
  • increase homozygous dominant and recessive.
  • decrease heterozygous genotype
28
Q

Effect of crossbreeding on gene frequency

A

increase heterozygote
- decrease homoezygote

increase genetic variation

29
Q

random genetic drift

A
  • random change due to chance
  • H-W assumes large populations
  • we with small populations
30
Q

what reduces risk of random genetic drift

A

increasing population size

31
Q

what is effective population (Ne)

A

effective number of breeding animals
Ne = 2 x number of mating pairs

32
Q

what is the equation of effective population

A

Ne=4NmNf / (Nm+Nf)

33
Q

what is mutation

A

biochemical change in DNA sequence
u = mutation rate from A(dominant) to a (recessive)
- u=1/25,000
v = mutation rate from a to A
- v = 1/250,00

34
Q

What is migration

A

introduction of alleles from outside the population
- Natural migration
- Artificial migration eg crossbreeding

35
Q

why do animal breeding carry out selection

A

for economically important traits
- quantitative
- qualitative

36
Q

what are qualitative traits

A

controlled by single gene

37
Q

what are quantitative traits:

A

controlled by many genes

38
Q
A
39
Q
A
40
Q
A