Genes by Cancer Type

Question 1

What myRisk genes are associated with breast cancer? (11)

Answer 1

BRCA1, BRCA2, TP53, PTEN, STK11, CDH1, PALB2, CHEK2, ATM, NBN, BARD1

Question 2

What myRisk genes are associated with ovarian cancer? (12)

Answer 2

BRCA1, BRCA2, MLH1, MSH2, MSH6, PMS2, EPCAM, TP53, STK11, BRIP1, RAD51C, RAD51D

Question 3

What myRisk genes are associated with colorectal cancer? (24)

Answer 3

MLH1, MSH2, MSH6, PMS2, EPCAM, APC, MUTYH (Biallelic & Monoallelic), TP53, PTEN, STK11, CHD1, BMPR1A, SMAD4, CHEK2, POLD1, POLE, GREM1, AXIN2, GALNT12, RPS20, RNF43, NTHL1 (Biallic), MSH3 (Biallelic)

Question 4

What myRisk genes are associated with endometrial cancer? (8)

Answer 4

MLH1, MSH2, MSH6, PMS2, EPCAM, TP53, PTEN, STK11

Question 5

What myRisk genes are associated with melanoma? (6)

Answer 5

BRCA2, CDKN2A (p16INK4a), CDKN2A (p14ARF), CDK4, TP53, PTEN

Question 6

What myRisk genes are associated with pancreatic cancer? (16)

Answer 6

BRCA1, BRCA2, MLH1, MSH2, MSH6, PMS2, EPCAM, APC, CDKN2A (p16INK4a), CDKN2A (p14ARF), CDK4, TP53, STK11, BMPR1A, SMAD4, ATM

Question 7

What myRisk genes are associated with gastric cancer? (11)

Answer 7

MLH1, MSH2, MSH6, PMS2, EPCAM, APC, TP53, STK11, CDH1, BMPR1A, SMAD4

Question 8

What myRisk genes are associated with prostate cancer? (10)

Answer 8

BRCA1, BRCA2, MLH1, MSH2, MSH6, PMS2, EPCAM, TP53, NBN, HOXB13

Question 9

What myRisk genes are associated with other cancers? (12)

Answer 9

MLH1, MSH2, MSH6, PMS2, EPCAM, APC, MUTYH (Biallelic), TP53, PTEN, CHD1, BMPR1A, SMAD4

Question 10

What cancers are associated with Hereditary Breast and Ovarian Cancer syndrome (HBOC)?

Answer 10

Breast, Ovarian, Pancreatic, Prostate

Question 11

What cancers are associated with Lynch syndrome/ Hereditary Non-Polyposis Colorectal Cancer (HNPCC)?

Answer 11

Ovarian, Colorectal, Endometrial, Pancreatic, Gastric, Prostate, Other

Question 12

What cancers are associated with Familial Adenomatous Polyposis (FAP) and Attenuated Familial Adenomatous Polyposis (AFAP)?

Answer 12

Colorectal, Pancreatic, Gastric, Other

Question 13

What cancers are associated with MUTYH-associated Polyposis syndrome (MAP) and MUTYH-associated Colorectal Cancer Risk?

Answer 13

Colorectal, Other

Question 14

What cancers are associated with Melanoma-Pancreatic Cancer Syndrome (MPCS) and Melanoma Cancer Syndrome (MCS)?

Answer 14

Melanoma, Pancreatic

Question 15

What cancers are associated with Li-Fraumeni Syndrome (LFS)?

Answer 15

Breast, Ovarian, Colorectal, Endometrial, Melanoma, Pancreatic, Gastric, Prostate, Other

Question 16

What cancers are associated with PTEN Hamartoma Tumor Syndrome (PHTS)?

Answer 16

Breast, Colorectal, Endometrial, Melanoma, Other

Question 17

What cancers are associated with Peutz-Jeghers Syndrome (PJS)?

Answer 17

Breast, Ovarian, Colorectal, Endometrial, Pancreatic, Gastric

Question 18

What cancers are associated with Hereditary Diffuse Gastric Cancer Syndrome (HDGC)?

Answer 18

Breast, Colorectal, Gastric

Question 19

What cancers are associated with Juvenile Polyposis Syndrome (JPS) and Hereditary Hemorrhagic Telangiectastia (HHT)?

Answer 19

Colorectal, Pancreatic, Gastric, Other