Genes and protein and the genetic code key words Flashcards

1
Q

Section of DNA on a chromosome that controls a feature by coding for formation of one or more specific polypeptides or a functional RNA (including rRNA and tRNA)

A

Gene

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2
Q

A thread like structure made of protein and DNA by which hereditary information is physically passed from one generation to the next

A

Chromosome

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3
Q

The material that makes up chromosomes. It consists of DNA and the protein histone

A

Chromatin

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4
Q

A chromosome which is not a sex chromosome

A

Autosome

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5
Q

The sequence of triplets of nucleotides (codons) in DNA which determines the sequence of amino acids in an organism’s proteins. It is degenerate; non-overlapping; universal; has start and stop codons

A

Genetic code

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6
Q

A single amino acid may be coded for by more than one triplet code

A

Degenerate

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7
Q

Each base appears in only one triplet - each bases is only read once

A

Non-overlapping

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8
Q

The genetic code is the same in all organisms - this is indirect evidence for evolution

A

Universal

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9
Q

Proteins, which together with DNA, make up the chromosomes of eukaryotic cells

A

Histones

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10
Q

Each of the two thread-like strands into which a chromosome divides that are joined together by a single centromere prior to cell division

A

Chromatid

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11
Q

The specific linear position of a particular gene on a certain chromosome

A

Locus

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12
Q

Alternative forms of a particular gene with different base sequences, and therefore different codes

A

Alleles

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13
Q

The process by which the genetic code codes for proteins in the cell. The template strand of DNA codes for mRNA in transcription, which is then translated into an amino acid sequence at the ribosomes

A

Protein synthesis

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14
Q

The complete set of genetic material present in a cell or an organism

A

Genome

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15
Q

The complete set of genes in a cell, including those in mitochondria and/or chloroplasts

A

Human genome

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16
Q

The full range of proteins produced by the genome. This is sometimes called the complete proteome, in which case the term proteome refers to the proteins produced by a given type of cell under a certain set of conditions

A

Proteome

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17
Q

Formation of messenger RNA molecules from the DNA that makes up a particular gene. It is the first stage of protein synthesis

A

Transcription

18
Q

Enzyme that joins tofether nucleotides to form messenger RNA during transcription

A

RNA polymerase

19
Q

Complex chemicals made up of an organic base, a sugar and a phosphate. They are the basic units of which the nucleic acids DNA and RNA are made

A

Nucleotides

20
Q

The type of RNA that is a long strand arranged in a single helix and its base sequence is determined by the sequence of bases on a length of DNA

21
Q

A sequence of three bases in DNA

22
Q

The strand of DNA which is used during transcription to make mRNA. It runs in a 3’ to 5’ direction so the mRNA is built in a 5’ to 3’ direction

A

Template strand

23
Q

A sequence of three adjacent nucleotides in mRNA that codes for one amino acid

24
Q

Portions of DNA within a gene that do not code for a polypeptide. They are removed from pre-messenger RNA after transcription

25
Portions of DNA within a gene that codes fro proteins. They are joined together during splicing
Exon
26
The process by which base sequences corresponding to the introns are removed and the functional exons are joined together
Splicing
27
The latter part of protein synthesis when the mRNA is used as template to which complementary tRNA molecules attach and the amino acids link to form a polypeptide
Translation
28
The type of RNA made of around 80 nucleotides and has an anticodon, which is complementary to a section of mRNA. Each molecule is specific to one amino acid
tRNA
29
A sequence of three adjacent nucleotides on a molecule of transfer RNA that is complementary to a particular codon on a messenger RNA molecule
Anti-codon
30
An organelle consisting or rRNA and proteins found in large numbers in the cytoplasm and on the RER of living cells. They bind to mRNA and use tRNA to synthesise polypeptides
Ribosome
31
A polymer consisting of a large chain of amino acids bonded together by peptide bonds
Polypeptide
32
A change to one or more nucleotide bases in DNA that could result in a change in genotype which may be inherited
Gene mutation
33
If a nucleotide is changed in the DNA sequence
Subsititution mutation
34
If the base change results in the formation of a stop codon
Nonsense mutation
35
If the base change results in a code for a different amino acid completely
Mis-sense mutation
36
If the base change still codes for the same amino acid as before (as code is degenerate)
Silent mutation
37
If a nucleotide is lost from the DNA sequence, resulting a 'frame shift' in translation
Deletion mutation
38
A material or other factor which increases the normal mutation rate, e.g. high energy radiation, chemicals
Mutagen (mutagenic agent)
39
A change that occurs in a chromosome. These changes are most often brought on by problems that occur during meiosis and can result in changes in the number of chromosomes in a cell or changes in the structure of a chromosome
Chromosome mutation
40
The process of the genome doubling that gives rise to organisms with multiple sets of chromosomes
Polyploidy
41
The failure of one or more pairs of homologous chromosomes or sister chromatids to separate normally during nuclear division, usually resulting in an abnormal distribution of chromosomes in the daughter nuclei
Non-disjunction