Generalidades Flashcards
What is the myocardium composed of?
Células musculares estriadas conectadas por uniones comunicantes
What are sarcomeres?
La unidad de contracción muscular formada por estructuras que se repiten en serie
What proteins are involved in muscle contraction?
Actina, miosina, troponina y tropomiosina
What role does tropomyosin play in relaxed muscle?
Impide la interacción entre actina y miosina
In a cross-section, how are thick and thin filaments arranged?
Cada filamento grueso está rodeado por seis filamentos finos
What are the dark and light bands in muscle fibers called?
Bandas oscuras (A) y bandas claras (I)
What is the Z line in a sarcomere?
Punto de unión entre los filamentos finos de una sarcómera con los de la sarcómera adyacente
What happens to the A band and I band during muscle contraction?
La banda A no varía de longitud; la banda I se acorta
What are T-tubules?
Invaginaciones de la membrana de la célula muscular estriada hacia el citosol
What triggers calcium release from the sarcoplasmic reticulum?
La propagación del potencial de acción a través de los túbulos T
What is the role of calcium in muscle contraction?
Se une a la troponina C, lo que permite la interacción entre actina y miosina
What are the two consequences of calcium influx in cardiac muscle?
- Mayor duración de la contracción del músculo cardíaco
- Mayor sensibilidad a la concentración de calcio
What happens during muscle relaxation in cardiac muscle?
El calcio se almacena en el retículo sarcoplasmático a través de una bomba ATPasa
Fill in the blank: ATP is required for _______.
disociar actina y miosina
True or False: The energy expenditure occurs during muscle contraction.
False
What is the function of the Na+/Ca2+ exchanger during relaxation?
Permite que una pequeña proporción de calcio salga al exterior
What does the term ‘zona H’ refer to in a sarcomere?
Zona en la banda A donde no existen filamentos finos
What happens to the sarcomeres during contraction?
Se acortan debido al deslizamiento de los filamentos de actina hacia el centro de la banda A
What is the main function of the heart?
To receive and pump blood to various organs and tissues of the body.
Where does deoxygenated blood enter the heart?
Through the superior and inferior vena cava and coronary sinus.
What is the pathway of blood starting from the right atrium?
Right atrium → Tricuspid valve → Right ventricle → Pulmonary valve → Pulmonary artery.
What happens to blood in the pulmonary bed?
Blood gets oxygenated.
What is the pathway of oxygenated blood starting from the pulmonary veins?
Pulmonary veins → Left atrium → Mitral valve → Left ventricle → Aortic valve → Systemic circulation.
What are the phases of the cardiac cycle?
Isovolumetric contraction, ejection period, isovolumetric relaxation, filling phases.
What initiates systole in the cardiac cycle?
Contraction of the ventricles.
What is the first heart sound associated with?
Closure of the AV valves.