General Virology Flashcards
What is a virus at the genetic level ?
Parasite
The virus is ?
The smallest infectionus agents (20-300nm)
Why viruses are obligatory intracellular ?
Because they have no metabolic activity
What organisms can the virus infect?
All organisms (animals, plants, and bacteria).
What is the name of the planet’s virus ?
Include complete viruses and Viroid (only nucleic acid ,without protein coat)
How can i see the virus ?
Only by electron microscope, except (poxviruses)
Are viruses can have both nucleic acids ?
No, it contains (DNA or RNA) never both
The capsid is made of
Substance called capsomeres
Functions of viral capsid
1_ protection.
2_ attachment.
3_ antigenic.
4_ morphology of virus (symmetry)
The Genome is ?
Viral nucleic acid = the infectious part of the virus.
STAGES OF VIRUS Replication
1_ Attachment or adsorption.
2_ Penetration (internalization) , (non-enveloped = endocytosis) or (enveloped = fusion).
3_ Uncoating.
4_ Eclipse.
5_ intracellular viral synthesis.
6_ Assembly (morphogenesis) nucleic acid + protein capsid = virions
7_ Release (lysis) or (buding).
What are the ways to cultivate the virus?
1_ Cell culture (tissue culture).
2_ Embryonated eggs.
3_ Laboratory animals (intact animals).
Fate of viral infections
1_ Inapparent or subclinical.
2_ Apparent infection (Disease).
3_ Persistent viral infections (chronic).
4_ Latent viral infections (dormant form).
5_ Slow viral infections (long incubation periods).