Candida Flashcards
What is the most important species of Candida?
Candida albicans
The surrounding environment of Candida?
especially at low incubation temperature and on nutritionally poor media.
What is the morphology of Candida albicans?
Gram positive, unicellular oval organism, pseudohyphae, budding yeasts
What is the normal habitat of Candida albicans ?
It is a normal flora of:
1_ oral cavity.
2_ gasteointestinal tract.
3_ female genital tract.
- sometimes the skin.
What is the name of the disease caused by Candida?
Candidiasis (moniliasis)
How The infection of Candida is transmissions?
1_ usually endogenous
2_ cross-infection (from mother to baby)
What factors predisposing to Oral Candidiasis ?
1_ changes in oral microbial flora.
2_ chronic local irritant, eg: ill-fitting appliances.
3_ Heavy smoking.
4_ malnutrition.
5_ immunological and endocrine disorders, as: diabetes.
6_ extremes of age.
7_ radiation to the head and neck.
8_ malignant and chronic diseases.
Classification of oral Candidiasis
Primary oral Candidiasis
Secondary oral Candidiasis
Clinical features of Oral Candidiasis.
- Acute pseudomembranous candidiasis
- Acute atrophic candidiasis
- Chronic atrophic candidiasis
- Angular cheilitis
- Chronic hyperplastic candidiasis (Candida leukoplakia)
Examples of oral Candidiasis
1_ Denture-induced stomatitis.
2_ Angular stomatitis and cheilitis.
3_ median rhomboid glossitis.
Laboratory diagnosis of oral candidiasis.
1_ Take swabs accurately from the lesion, or
Take biopsy in candida leukoplakia.
2_ Gram stained, see the characteristics morphology.
3_ In Culture.
The culture of Candida albicans
1_ selective medium for Candida, Sabouraud’s Dextrose Agar (SDA).
37°C . in aerobic conditions. 1-2 days
2_ Germ tube test, for C. albicans.
37°C . 1-2 hours
Treatment of oral candidiasis.
1_ Correct the predisposing factors, if possible.
2_ improve the general health of patient.
3_ Topical nystatin is given, as: lozenges or pastilles.
4_ Azole group of antifungal agents, as: fluconazole oral gel.
