General Surgery Flashcards
what is an enterocutaneous fistula?
link intestine to skin
may be high (>500ml) or low (<250ml) output depending on source
duodenal/ jejunal fistulae tend to be high vol, electrolyte rich secretions -> severe excoriation of the skin
colo-cutaneous fistulae -> leak faeculant material
what is an enterovesicular fistula?
fistula between intestine and bladder
- > frequent UTIs
- > passage of gas from urethra during urination (bubbly urine ie. pneumaturia)
Mx of high output fistula?
octreotide -> reduces the vol of pancreatic secretion
nutritional complicatoins common -> may necessitate use of TPN
protect overlying skin using a well fitted stoma bag
What is Goodsall’s rule?
it means that anterior-opening fistulas tend to follow a simple, direct course while posterior-opening fistulas may follow a devious, curving path with some even being horseshoe-shaped before opening in the posterior midline
mx of inguinal hernias?
clinical consensus is treat medically fit patients even if they are asymptomatic
- mesh repair assoc w lowest recurrence rate
a hernia truss: for pts not fit for surgery
pigmented gallstones assoc w?
sickle cell anaemia
-> results in increased red cell haemolysis and thus pigmented gallstone
pigmented gallstones are primarily made of bilirubin
A 65-year-old man with a history of dyspepsia is found to have a gastric MALT lymphoma on biopsy. What treatment should be offered?
Eradicate H pylori
In meckel’s diverticulitis, why is pain worse after meals?
contain ectopic gastric mucosa which may secrete acid with subsequent bleeding and ulceration.
what happens in Dumping syndrome?
early: food of high osmotic potential moves into small intestine -> fluid shift into the lumen, can cause pain due to lumen distension and diarrhoea
later: surge of insulin following food of high glucose value in small intestine - 2-3h later the insulin overshoots and causes hypoglycaemia
features of oesophagitis causing oesophageal bleeding?
small vol of fresh blood, often streaking vomit
often ceases spontaneously.
usually +ve hx of antecedent GORD type symptoms
features of oesophageal ca causing bleeding?
usually small vol of blood, except as pre terminal event w erosion of major vessels
often assoc w symptoms of dysphagia and constitutional symptoms (FLAWS)
may be recurrent until malignancy managed
features of Mallory Weiss tear causing bleed?
typically brisk small to mod volume of bright red blood following bout of repeated vomiting
melaena rare
usually ceases spontaneously
features of oesophageal varices?
usually large vol of fresh blood
swallowed blood can cause melaena
often assoc w haemodynamic compromise
may stop spontaneously but rebleeds are common until appropriately managed
feautres of gastric cancer causing bleed?
may be frank haematemesis or altered blood mixed w vomit
usually prodromal features of dyspepsia and may have constitutional symptoms
amount of bleeding variable but erosion of major vessel may produce considerable haemorrhage
features of Dielafoy lesion causing bleed?
often no prodromal features
this AV malformation may produce considerable haemorrhage and may be difficult to detect endoscopically
features of diffuse erosive gastritis causing bleeding?
usually haematemesis and epigastric discomfort
usually underlying cause such as NSAID use
large vol haemorrhage may occur w considerable haemodynamic compromise
Upper GI bleed in pt with previous hx of AAA surgery?
aorto-enteric fistulation
- rare but impt cause of major haemorrhage assoc w high mortality
most common cause of major haemorrhage from upper GI bleed?
posteriorly sited duodenal ulcer
when should pts admitted w upper GI bleed undergo upper GI endoscopy?
ideally ALL should undergo endoscopy within 24h of admission
in those who are unstable, this should occur immediately after resus or in tandem w it.
may be safer to perform endoscopy in theatre w an anaethetist present.
Mx of suspected oesophageal varices?
should receive terlipressin before endoscopy
during endoscopy: varices banded or subjected to sclerotherapy
if this is not possible due to active bleeding -> Sengstaken-Blakemore tube inserted
portal pressure should be lowered by combination of medical therapy +/- TIPSS
what to rmb about sengstaken blakemore tube?
gastric balloon inflated first then oesophageal balloon
balloon needs deflating after 12 h (ideally sooner) to prevent necrosis
mx of upper GI bleed due to erosive oesophagitis/ gastritis?
Proton Pump Inhibitor
Identifiable bleeding points should receive combination therapy of injection of adrenaline and either a thermal or mechanical treatment
pts w diffuse erosive gastritis who cannot be managed endoscopically and cont to bleed may require gastrectomy
mx of bleeding ulcers that cannot be controlled endoscopically?
laparotomy and ulcer underrunning
Blatchford and Rockall scores in Upper Gi bleeds?
Blatchford score assesses severity of upper GI bleed, and thus need for admisison and timing of endoscopic intervention
(1 or more = high risk)
Rockall score: determined following endoscopy to assess risk of rebleeding and mortality
duodenal ulcer has caused upper GI bleed, if bleeding is brisk and ulcer is posteriorly sited, what artery is affected?
gastroduodenal artery
surgical mx of bleeding gastric ulcer?
- Under-running of the bleeding site
- Partial gastrectomy-antral ulcer
- Partial gastrectomy or under running the ulcer- lesser curve ulcer (involving left gastric artery)
- Total gastrectomy if bleeding persists
Post cystectomy
Which investigation should you order to offer the most definitive result to assess whether the bladder suture line has healed?
Cystogram:
passing radiopaque dye into the bladder, then performing radiographs to assess the course of the bladder contents. This provides evidence of whether there is any radiopaque fluid that has escaped the bladder and is free in the abdominal cavity.
mutation of PTEN gene
macrocephaly
multiple intestinal hamartomas
multiple trichilemmomas
high risk of cancer (breast, thyroid, uterine, colorectal)
Cowden disease
mx of haemothorax when >1.5L blood loss initially or losses of >200ml per hour for >2 hours?
thoracotomy (surgical incision into chest wall)
- allow for surgical exploration and closure of any actively bleeding sites.
what is Parklands formula for burns?
4ml * % body surface area * weight (kg) = ml of Hartmann’s to be given in first 24 hours
give first half in 8h
what are the boundaries of the Hesselbachs triangle?
Boundaries of Hesselbach’s Triangle
Medial: Rectus abdominis
Lateral: Inferior epigastric vessels
Inferior: Inguinal ligament
Hernias occurring within the triangle tend to be direct and those outside - indirect.
what nerve is at risk during carotid endarterectomy?
ipsilateral hypoglossal nerve.
The hypoglossal nerve supplies ipsilateral motor component to the tongue and the hyoid depressors.
tongue will deviate towards the affected side
what nerve is at risk during posterior approach to hip for transplant?
sciatic nerve
what nerve is at risk during inguinal hernia surgery?
ilioinguinal nerve
what nerve is at risk of damage following varicose vein surgery?
sural and saphenous nerves
what nerve is at risk of damage following Axillary node clearance?
long thoracic nerve, thoracodorsal nerve and intercostobrachial nerve.
what nerve is at risk of damage during Anterior resection of rectum?
hypogastric autonomic nerve
what nerve is at risk of damage following thyroidectomy?
laryngeal n
what nerve is at risk of damage with Lloyd Davies stirrups?
common peroneal nerve
what nerve is at risk of damage following Posterior triangle lymph node biopsy?
accessory n
best ix for hydatid cyst?
CT is the best investigation to differentiate hydatid cysts from amoebic and pyogenic cysts.
Surgery is the mainstay of treatment (the cyst walls must not be ruptured during removal and the contents sterilised first).
what would result in hyperacute rejection of an organ transplant?
ABO incompatibility
- due to pre existing antibodies to other groups
- renal transplants at greatest risk
what would cause acute rejection of organ transplant?
all organs may undergo this.
occurs during first 6 months, usually T cell mediated.
usually mononuclear cell infiltrates
increased risk if HLA mismatching
what causes chronic rejection of organ transplant?
any.
occurs > 6 months
vascular changes predominate -> organ ischaemia
HLA mismatch increases risk
how is donor kidney transplanted into recipient?
operation performed under GA
- Rutherford-Morrison incision
- > provides excelled extraperitoneal access to iliac vessels
the external iliac artery and vein are dissected out and following systemic heparinisation are cross clamped
vein and artery are anastamosed to the iliacs and the clamps removed
-> ureter then implanted into bladder and stent placed to maintain patency
in the immediate phase, what common problem is encountered in cadaveric kidneys which tends to resolve?
acute tubular necrosis
what are graft survival times like from live donors vs cadaveric donors?
live donors: 25 yrs
cadaveric donors: 9 yrs
mx of Infantile umbilical hernia
vast majority resolve without intervention before age 4-5
what is the first major branch of the abdominal aorta?
celiac trunk
what does the coeliac trunk supply?
supplies liver, stomach, abdominal oesophagus, spleen and superior half of duodenum and pancreas
what does the coeliac trunk divide into?
3 branches
- left gastric -> oesophagus, stomach
- common hepatic artery -> liver, + gastroduodenal artery (duodenum)
- splenic artery -> spleen, pancreas
what is the second major branch of the abdominal aorta?
superior mesenteric artery
what does the superior mesenteric artery supply?
intestine from lower part of duodenum to 2/3rds of transverse colon
+ pancreas
what are the branches of the superior mesenteric artery?
inferior pancreaticoduodenal artery: head of pancreas + inferior parts of duodenum
intestinal arteries: branches to ileum and jejunum
ileocolic artery: last part of ileum, caecum and appendix
right colic artery: to ascending colon
middle colic artery: transverse colon
what is the third major branch of the abdominal aorta?
inferior mesenteric artery
what does the inferior mesenteric artery supply?
large intestine from splenic flexure to upper part of the rectum
what are the watershed areas in the colon?
splenic flexture (between IMA and SMA)
sigmoid colon and rectum
during times of systemic hypoperfusion, such as in disseminated intravascular coagulation or heart failure, these regions are particularly vulnerable to ischemia because they are supplied by the most distal branches of their arteries, and thus the least likely to receive sufficient blood
mx of splenic trauma?
if major haemorrhage, and hilar injuries
splenic resection
mx of splenic trauma if mod haemodynamic compromise, tears or lacerations affecting < 50% of spleen, increased amounts of intra abdo blood?
laparotomy with conservation
mx of splenic trauma w no hilar disruption, minimal intra abdo blood, small subcapsular haematoma?
conservative
mx of congenital inguinal hernia?
Indirect hernias resulting from a patent processus vaginalis
Should be surgically repaired soon after diagnosis as at risk of incarceration
what is spondylolisthesis?
spontaneous displacement of a lumbar vertebral body upon the segment below it
usually displacement forward at the L4/5 or L5/S1 level
may be asymptomatic or -> chronic pain w sciatica, worse on standing
palpable step of the displaced vertebral body will be felt on examination of spine
mx of spondylolisthesis?
if asymptomatic: no tx required
severe pain is indication for surgical release of affected nerves w fusion of the spinal column
what is spondylosis?
osteoarthritis of the spine
disc degeneration -> lumbar instability
aching pain worse on activity and in mornings
O/E may be some restrictions of spinal movements
what is marjolins ulcer?
development of a squamous cell carcinoma occuring in an area of scarred or traumatized skin e.g. burns, chronic wounds, venous ulcers
lesions appear as raised, fleshy, firm papules that grow slowly
tx: wide local excision
risk factors for Basal cell carcinomas ie. rodent ulcer?
UV light exposure
xray exposure
chronic scarring
genetic predisposition
male sex
small, skin coloured papules w telangiectasia and a pearly edge w central necrosis?
Basal cell carcinoma
locally invasive, destroying soft tissue, cartilage ad bone
metastasis is v rare
mx via surgical excision
what is a cystic hygroma?
congenital benign proliferation of lymph vessels found in posterior triangle of the neck
multicystic swelling that is fleshy and compressible and contains clear fluid
transilluminates brightly
what is frozen shoulder?
adhesive capsulitis
relatively common
frequently follows hx of minor trauma
long hx of aching pain and restriction of all glenohumeral movements
external rotation is first to be restriction
three characteristic phases: freezing (pain), frozen (stiffness), thawing
impingement syndrome -> pain on abduction between which angles?
60 to 120
what is the most common site for rotator cuff tear?
‘critical zone’ of the supraspinatus tendon, a relatively avascular region near its insertion
-> shoulder tip pain and inability to abduct the arm
localised tenderness at lateral margin of the acromion
popeye sign
elbox flexion produces unusual bulge
-> long tendon of biceps rupture
mx of myxoedema coma?
intensive care for fluids, gentle rewarming and IV thyroid hormones
mx of thyroid storm?
mx in intensive care with fluids, gentle cooling and intravenous beta-blockers (propranolol)
Sodium iopodate (which inhibits thyroxine release) and carbimazole (inhibits synthesis of thyroxine) are also administered.
Histological analysis demonstrates a characteristic ‘Orphan Annie eye’ appearance nuclei
papillary thyroid ca
route of spread of thyroid cancers?
Papillary -> Yellow -> Lymph
Follicular -> Red -> Blood
Medullary -> Yellow -> Lymph
Anaplastic -> Combined -> Lymph and blood
what side do diaphragmatic ruptures typically occur on?
L side
-liver protective on the right
Following diaphragmatic rupture, the abdominal contents herniate into the thorax. Features therefore include respiratory compromise.
ix of suspected ruptured spleen?
Stable patients can undergo CT, whereas unstable patients require urgent laparotomy.
post splenectomy prophylaxis?
vaccinations for the three main encapsulated organisms that are usually destroyed by the spleen (Streptococcus pneumoniae, Haemophilus influenzae B and Neisseria meningitides), with boosters at 10 years
what are the Lanz and Giridion incisions used for?
to access theappendix, predominantly for appendicetomy
Both incisions are made at McBurney’s point (two-thirds from the umbilicus to the ASIS)
Lanz incision is a transverse incision, whilst the Gridiron incision is oblique
Due to its continuation with Langer’s lines, the Lanz incision produces much more aesthetically pleasing results with reduced scarring.
midline incision what surgery?
wide array of abdominal surgery, as it allows the majority of the abdominal viscera to be accessed.
A midline laparotomy can run anywhere from the xiphoid process to the pubic symphysis, passing around the umbilicus
this incision causes minimal blood loss or nerve damage, and can be used for emergency procedures. Its positioning however does make it susceptible to significant scars.
what is a paramedian incision used for?
rare
used to access much of the lateral viscera, such as the kidneys, the spleen, and the adrenal glands.
incision runs 2-5cm lateral to the midline
A paramedian incision can damage the muscles’ lateral blood and nerve supply, which may result in the atrophy of the muscle medial to the incision.
what is a Kocher incision used for?
subcostal incision used to gain access for the gall bladder the biliary tree.
incision is made to run parallel to the costal margin, starting below the xiphoid and extending laterally
2 extensions possible: rooftop/ mercedes benz
Left- sided incisions are used for splenectomy.
The incision cannot be extended medially and, if it is extended too far laterally, many intercostal nerves can be damaged.
what is a rooftop incision used for?
oesophagectomy, gastrectomy, bilateral adrenalectomy, hepatic resections, or liver transplantation
what are langers lines?
Langer’s lines mark the principle axis of orientation of the collagen fibres of the dermis and form the natural creases of the skin. Incisions that are made parallel to these lines offer the best cosmetic outcome.
pain, erythema and palpable cord-like structure around a cannula?
superficial thrombophlebitis
mx by removing the cannula, elevate limb and NSAIDs for pain
surgical mx of varicose veins along the long saphenous vein?
saphenofemoral ligation:
long saphenous vein stripped to knee and all its branches ligated
surgical mx of varicose veins along short saphenous vein?
saphenopopliteal ligation
***surgery for varicose veins only work if deep venous system is intake
what layers are cut during a midline incision?
Skin -> Campers fascia -> Scarpa’s fascia -> linea alba -> transversalis fascia -> extraperitoneal fat -> peritoneum
e.g.s of emergency midline laparotomy?
perforated duodenal ulcer
trauma
ruptured AAA
Hartmann’s
e.g.s of elective midline laparotomy?
colectomy
AAA
Hiatus hernia repair
advantages of midline laparotomy?
good access
almost bloodless line as relatively avascular
no muscle fibres divided
minimal nerve + muscle injury
can be quickly made and closed
disadvantages of midline laparotomy?
long midline scar crossing Langer’s lines so poor cosmetic appearance
more painful than transverse incisions
lower midline incision lacks posterior rectus sheath so urinary bladder may be injured
what is Jenkin’s rule of closure?
length of suture = 4 x length of incision, 1cm bite, 1cm apart -> lower risk of dehiscence
what is a paramedian scar?
scar resulting from vertical incision 2.5cm from midline L/R
can extend from costal margin to pubis
advantages of paramedian incision?
provides access to lateral structures
rectus muscle not divided (rectus sheath cut, rectus displaced laterally)
secure closure
can be extended by a curvilinear incision towards xiphoid process if required (Mayo-Robson incision)
disadvantages of paramedian scar?
longer to make and close
incision needs to be closed in layers
tends to strip muscles of lateral blood and nerve supply resulting in atrophy of muscle medial to incision
what is a Battle’s incision? why is it not used anymore?
not used due to damage to nerves entering rectus sheath and poor healing
causing incisional hernias
what is a Mercedes Benz incision classically used for?
liver transplantation and diaphragmatic hernia repair
what layers are cut in Giridions/ McBurney’s incision?
skin -> Carper’s fascia -> Scarpa’s fascia -> external oblique -> internal oblique -> transversus -> transversalis fascia -> pre peritoneal fat -> peritoneum
disadvantages of Lanz incision or Giridions?
risk of injury to ilioinguinal and iliohypogastric nerves
may predispose to inguinal hernia post op (esp w Lanz)
laparoscopy scars?
generally 3-4 incisions
1 always at umbilicus to allow port for camera
others located in 1 of 4 quadrants for tools e.g. griper, cutting, dissecting scissors etc
Loin (lumbar) incision?
used for nephrectomy
what is a McEvedy’s incision?
transverse incision, 1cm above pubic symphysis and extends from midline laterally
gives access to Hesselbach’s triangle
-> emergency femoral hernia
*modified version replaced original incision which had a v high incisional hernia rate
what is an inguinal incision used for?
scar from oblique incision 1cm above and parallel to inguinal ligament, from inner to outer inguinal ring
for open inguinal hernia repair, orchidectomy, varicoceles, testicular ca
adv: follows Langer’s Lines
disadv: high rates of chronic neuropathic pain
what should the ideal incision allow for?
ease of access to desired structures
can be extended if needed
ideally muscles should be split rather than cut
heals quickly w minimal scarring
cosmetically pleasing