General Surgery Flashcards
middle aged adult + superficial unilateral hip pain that is exacerbated by external pressure to the upper lateral thigh
trochanteric bursitis
how does trochanteric bursitis present?
hip pain when pressure is applied (as when sleeping) and with external rotation or resisted abduction.
what is trochanteric bursitis?
inflammation of the bursa surrounding the insertion of the gluteus medius onto the femur’s greater trochanter
what population does slipped capital femoral epiphysis affect?
obese male children during late childhood or early adolescence
WHat nerves supply the upper lateral thigh causing superficial referred pain?
- lateral femoral cutaneous
2. iliohypogastric
By what mechanism does the following lower ICP?
Head elevation
increased venous outflow from the head
By what mechanism does the following lower ICP?
Sedation
decreased metabolic demand and control of HTN
By what mechanism does the following lower ICP?
Intravenous mannitol
Extraction of free water out of the brain tissue -> osmotic diuresis
By what mechanism does the following lower ICP?
Hyperventilation
CO2 washout leading to cerebral vasoconstriction
Cerebral blood flow increases via what mechanisms?
- Hypercapnia
- Increased metabolic demand
- Hypoxia through vasodilation
coag negative staph most commonly gains access to the blood via what??
indwelling femoral triple lumen catheter
femoral catheter infections are more commonly caused by what?
enteric organisms
how soon after the onset of a new drug do you see drug fever?
one to two weeks
drug fever is most commonly associated with what?
- Anticonvulsants
2. TMP-SMX
what is the most common presentation of intraductal papilloma?
a form of benign breast disease presents w intermittent bloody discharge from one nipple
what are the common causes of paralytic ileus?
- Exaggerated intestinal rxn after abdominal surgery
2. Retroperitoneal hemorrhage associated with vertebral fracturs
What does abdominal x-ray show in pts w paralytic ileus?
- air fluid levels
- distended gas-filled loops of both the small and large intesines
what is the tx of choice for paralytic ileus?
- bowel rest
- supportive care
- tx of secondary cause of the ileus
What is the cause of nursemaid elbow?
subluxation of head of radius at the elbow joint
what is the tx of nursemaid elbow?
Closed reduction:
- First extend and distract the elbow
- Supinate the forearm
- Hyperflex the elbow with your thumb over the radial head in order to feel the reduction as it occus
What is Kehr sign?
intraabdominal pathology causing peritonitis and irritation of the diaphragm
- irritation of the parietal peritoneum covering the undersurface of either hemidiaphragm can be referred to the ipsilateral shoulder bc the phrenic nerve originates from the C3-C5 spinal levels
what is the only part of the bladder covered by peritoneum and thus can cause peritonitis?
bladder dome
which part of the bladder is most susceptible to rupture and why?
- bladder dome
- the dome has a developmental hiatus where the urachus originates during embryonic life
what is the most common site of extraperitoneal bladder rupture?
bladder neck
What is the gold standard for evaluating mesenteric ischemia?
mesenteric angiography
what is the typical presentation of mesenteric ischemia?
severe abdominal pain after eating and relatively normal abdominal exam
what is the respiratory quotient?
the steady state ratio of carbon dioxide produced to oxygen consumption per unit time
what does a RQ close to 1 indicate? 0.8? 0.7?
1= carbohydrates are the major nutrient being oxidized
- 8 = proteins
- 7 = fatty acids
how is RQ important in mechanically ventilated patients?
- overfeeding, esp with carbs, causes excessive CO2 production and makes weaning from ventilation more challenging
- this is important in pts w preexisting lung disease as well
what is the RQ in sepsis? why?
less than 1, bc sepsis is a hypermetabolic hypercatabolic state where both fat and protein are broken down
what are the presenting sx of severe CO poisoning after smoke inhalation?
- COnfusion -> COma
- Wheezes
- Seizure
- Heart failure or arrythmias
what are the sx of moderate CO poisoning?
- HA
- Nausea
- Dyspnea
- Malaise
- Altered mentation
- Dizziness
how does one diagnose CO poisoning?
confirmed clinically and by documenting elevated carboxyhemoglobin level (>3% nonsmokers, >15% smokers)
tx of CO poisoning?
100% oxygen w facemask
DRE finds a tender, fluctuant mass palpable only with the tip of the examining finger?
abscess in the rectovesical pouch
What are the sx of a anorectal abscess compared to a rectovesical abscess?
Anorectal: perineal pain + fluctuant mass palpable on the perineum - pain w ambulation and defecation - urinary retention Rectovesical: lower abdominal pain - malaise, low grade fever - tender pelvic mass on rectal exam
if pt has signs of PAD and ABI is normal, what should be the next step?
exercise testing with repeat ABI
ABI of:
1-1.3
<0.4
1-1.3 = normal
50% occlusion in a major vessel
<0.4 = limb ischemia
Presenting signs of a posterior shoulder dislocation versus anterior?
Posterior: flattening of anterior shoulder
- prominent coracoid process
- arm held adducted and internally rotated, cannot externally rotate
Anterior: most common,
- pt holds arm abducted and externally rotated
what does radiograph show w posterior dislocation of shoulder?
- Light bulb sign: Internal rotation of humeral head with circular appearance
- Rim sign: widened joint space >6mm
- Trough line sign: 2 parallel cortical bon lines on the medial aspect of the humerus
what is a marjolin ulcer?
squamous cell carcinoma within burn wounds
what fibers are most often damaged in syringomyelia?
- spinothalamic tract (pain and temperature)
2. upper extremity motor fibers
what are the most common causes of syringomyelia?
- Arnold Chiari malformations
2. Previous spinal cord injuries: most often MVA w whiplash
what is the most sensitive finding for blunt aortic injury on radiograph?
mediastinal widening (in the setting of MVA or falls >10ft)
sx of compartment syndome?
- severe pain that is worsened on passive ROM
- Paresthesias
- Pallor
- Paresis
all of the affected limb
how do you diagnose compartment syndrome? tx?
use needle and pressure transducing catheter system
pressures >30mmHg may result in cessation of blood flow
- tx emergently by fasciotomy
what are postop measures used to decrease the risk of pneumonia?
all encourage lung expansion:
- Incentive spirometry* first line
- Deep breathing exercises
- CPAP
- Intermittent positive pressure breathing
what is the difference between pulmonary contusion and ARDS?
Pulmonary Contusion: within first 24hrs, unilateral
ARDS: 24-48 hours, bilateral
what is the tx for mastitis?
- Analgesics
- Antibiotics: Dicloxacillin or cephalosporin
- Continued nursing
What is Kehr sign?
Left shoulder pain referred from splenic hemorrhage irritating the phrenic nerve and diaphragm
what are the risk factors for nasopharyngeal carcinoma?
- EBV!!!!!!!! huge.
- Smoking
- Chronic nitrosamine consumption (diets rich in salted fish)
acute pain and swelling of the midline sacrococcygeal skin and subcutaneous tissues
pilonidal cyst infection
pilonidal cysts are most prevalent in whom?
young males with a lot of body hair
tx of pilonidal cysts?
drainage of abscesses and excision of sinus tracts
perianal fistulae are generally located where?
within 3cm of the anal margin
tx of duodenal hematoma?
- most resolve spontaneously in 1-2 weeks so just nasogastric suction and parenteral nutrition
in what population do you normally see acalculous cholecystitis?
Pt’s chronically hospitalized in the ICU with any:
- Multiorgan failure
- severe trauma
- Surgery
- Burns
- Sepsis
- Prolonged parenteral nutrition
what is the suspected pathogenesis of acalculous cholecystitis?
- Cholestasis and gall bladder ischemia ->
- Secondary infection by enteric organisms ->
- Edema of the gall bladder serosa ->
- Necrosis of the gall bladder
5 W’s of postop fever?
- Wound infection
- Wind (atelectasis)
- Water (UTI)
- Walking (DVT)
- Wonder drugs!
most common cause of postop fever within 1 day of surgery?
atelectasis
What is the workup for postop fever?
- CBC
- Blood and urine cultures
- Urinalysis
- CXR
how do you correct for low albumin in the setting of hypocalcemia?
Corrected Ca = 0.8 (normal albumin - observed albumin) + Observed Ca
in acidosis, what happens to the ionized fraction of Ca?
increases
in alkalosis what happens to the ionized fraction of Ca?
decreases
what are some causes of hypocalcemia?
- Acute pancreatitis
- Necrotizing fasciitis (massive soft-tissue infections)
- Acute/chronic renal failure
- Pancreatic/small bowel fistulas
- Severe alkalosis (decrease in ionized fraction)
what ECG changes does one observe in hypocalcemia?
prolonged QT interval
what are some causes of hypercalcemia?
- Hyperparathyroidism
- Cancer: breast & multiple myeloma
- Drugs (thiazides)
what is the biggest danger of TPN?
infection
estimations of basal energy expenditure (BEE): Nml Males: Nml Females: Nonstressed patient Postsurgery Trauma/sepsis/burns Fever
Nml Males: 25 kcal/kg/day Nml Females: 22 kcal/kg/day Nonstressed patient: BEE x 1.2 Postsurgery: BEE x 1.3-1.5 Trauma/sepsis/burns: BEE x 1.6-2.0 Fever: 12% increase per *C
what is the RQ of: Lipids- protein- carbs- balanced diet-
Lipids- 0.7
protein- 0.8
carbs- 1.0
balanced diet- 0.83
what is the RQ?
ratio of carbon dioxide released to oxygen consumed per unit metabolism of a substrate
what is the fuel for enterocytes? colonocytes? immune modulating agents?
Enterocytes: glutamine
Colonocytes: short chain fatty acids
Immune modulating: omega 3 fatty acids
causes of anion gap metabolic acidosis?
MUDPILES Methanol/metabolism errors Uremia Diabetic ketoacidosis Paraldehyde Iron/Isoniazid Lactic acidosis Ethylene glycol Salicylates
what are the 4 major processes that cause anion gap metabolic acidosis?
- Ketoacidosis
- Lactic acidosis
- Renal failure
- Intoxication
what are the causes of normal anion gap metabolic acidosis?
HARDUP Hyperparathyroidism Adrenal insufficiency/anhydrase inhibitors Renal tubular acidosis Diarrhea Ureteroenteric fistula Pancreatic fistulas
how do you calculate the anion gap?
AG = Na - (Cl + HCO3)
what are the two mechanisms of metabolic alkalosis?
- Loss of H+ from kidneys or GI tract
2. Gain of HCO3: TPN, PRBCs, lactated ringers
What are the causes of respiratory alkalosis?
MIS(HAP)3S Mechanical overventilation Increase in ICP Sepsis Hypoxia/hyperpyrexia/heart failure Anxiety/ascites/asthma Pregnancy/Pain/Pneumonia Salicylates
Barium swallow = corkscrew shaped
diffuse esophageal spasm
classic triad of achalasia?
- Dysphagia
- Regurgitation
- Weight loss
tx of choice for achalasia?
Heller’s myotomy: esophagomyotomy
what are the two false diverticula in the esophagus?
- Zenkers: pharyngoesophageal
- Epiphrenic
= pulsion diverticula
when would you tx asymptomatic zenkers diverticulum?
when it’s >2cm
tx of zenkers diverticulum?
- Cervical pharyngocricoesphageal myotomy (incising the cricopharyngeus
followed by:
- Diverticulopexy: larger diverticula
- Diverticulectomy: largest diverticula
how do you differentiate between postop ileus and postop bowel obstruction?
ileus = hypoactive or absent bowel sounds obstruction = hyperactive tinkling sounds
what are the causes of postop ileus following bowel surgery?
- Increased splanchnic sympathetic tone following violation of the peritoneum
- Local release of inflammatory mediators
- Postop narcotic use
poor glucose control can cause what bowel condition?
gastroparesis: characterized by early satiety, nausea, and postprandial vomiting
what antibiotic is used as a promotility agent?
erythromycin
what DA antagonist has promotility effect?
metoclopramide
what is morton neuroma?
not a neuroma- but is associated with pain between the 3rd and 4th toes on the plantar surface and a clicking sensation (Mulder sign) when simultaneously palpating this space and squeezing he joints
what is tarsal tunnel syndrome?
compression of the tibial nerve as it passes through the ankle
- caused by a fracture of the bones around the ankle
- sx = burning, numbness, and aching of the distal plantar surface of the foot or toes (and sometimes calf)
what is tenosynovitis?
inflammation of the tendon and its synovial sheath
- seen in hands and wrist joints following a bite or puncture wounds
- pain, esp w flexion and extension
what is tic douloureux?
trigeminal neuralgia- short bursts of excruciating, lancinating pain lasting from seconds to minutes in the distribution of the second and third branches of the trigeminal nerve.
- most likely external compression of the trigeminal nerve
what is strabismus?
improper alignment of the eyes
if you suspect a ruptured AAA in a pt, but theyre unstable for a CT scan, what can you do?
bedside ultrasound
what abnormal lab values do you see in acute pancreatitis?
- Elevated amylase and lipase
- Elevated WBC
- Mild azotemia
- Hocalcemia
major thoracic trauma + tachypnea + paradoxical thoracic wall movements that correct with positive pressure mechanical ventilation
Flail chest!
= multiple contiguous ribs are fractured in two or more locations
= hypoxemia + hyperventilation
tx of flail chest?
pain control and supplemental O2
+ intubation with mechanical positive pressure in most pts
EKG shows absent P waves, irregular rhythm, and inverted T waves, what is it?
A Fibb (T wave inversions could also be due to her longstanding HTN)
what is Legg-Calve-Perthes disease? classic presentation?
idiopathic avascular necrosis of the femoral capital epiphysis
- seen in boys 4-10 (5-7)
- classically presents as hip, groin or knee pain + an antalgic gait
what is the tx of legg-calve parthes disease?
usually conservatively with observation and bracing
surgery when the femoral head is not well contained with the acetabulum
what pt population is SCFE most likely to present in?
obese adolescent male with complaints of pain
How does osteosarcoma usually present on radiograph?
Codman’s triangle in metaphyses of long bones
How does Ewings sarcoma present on radiograph?
tumor seen within diaphyses of long bones
Pt w recent cardiac surgery presents with fever, tachycardia, chest pain, leukocytosis, and sternal wound drainage or purulent discharge.
Acute mediastinitis!
- due to intraoperative wound contamination
what does CXR show in acute mediastinitis?
a widened mediastinitis
tx of acute mediastinitis?
surgical debridement with immediate closure and prolonged antibiotic therapy
when does postoperative acute mediastinitis usually present?
within 14 days of the surgery
when does postpericardiotomy syndrome present? tx?
a few weeks following a procedure with pericardium incision
tx: NSAIDs and pericardial puncture if tamponade occurs
what population is most prone to developing acute bacterial parotitis?
- Dehydrated post-operative patients
2. Elderly
pt presents w flaccid paralysis after aortic surgery?
spinal cord ischemia- rare complication of vascular surgery
what is the artery of adamkiewicz?
the most prominent thoracic radicular artery and arises from the aorta to supply the anterior spinal arteries in the T9-T12 region
- thus this artery is susceptible during thoracic surgery, causing spinal cord ischemia and flaccid paralysis
what are the risk factors for spinal cord infarction in a pt undergoing thoracic AA repair?
- Hypotension in the perioperative period
- Increased spinal canal pressure
- Aortic cross clamping or occlusion
how do pts w spinal cord ischemia usually present?
- Abruptly onset flaccid paralysis
- Bowel/bladder dysfxn
- Sexual dysfxn
- possible hypotension
- Loss of tendon reflexes
what is the next step when spinal cord ischemia is suspected?
- Emergent MRI
2. supportive care and lumbar drains to reduce spinal pressure
what is the pressure threshold to perform escharotomy in burn victims w compartment syndrome?
25-40mm Hg
what is the most commonly injured nerve in fracture of midshaft of the humerus?
radial nerve
what imaging modality is used to see uric acid stones?
CT scan! theyre radiolucent
what is Volkmann’s ischemic contracture?
the final sequel of compartment syndrome in which the dead muscle has been replaced with fibrous tissue
pt postop rhinoplasty develops whistling noise during respiration??
nasal septal perforation- usually from a septal perforation or a septal abscess
what is the definition of oliguria in someone w/out preexisting intrinsiv kidney disease?
<6cc/kg
per day
what are the steps in management of suspected prerenal azotemia?
- Change foley catheter
2. Careful fluid challenge (bolus IV fluids)
what is the most common bone in the body to be affected by stress fractures?
Tibia
when do you typically see postop atelectasis at its worst?
second postop day and can last up to 5days!
what are the common CXR radiographic findings in esophageal rupture?
- Pleural effusion (usually l sided)
- Pneumomediastinum
- Pneumothorax
what is the test of choice for diagnosing esophageal perforation/rupture?
water soluble esophagram
What are the signs for an AAA?
- Profound hypotension
- Abdominal or back pain
- Syncope
- Pulsatile mass
What are the symptoms of fat embolism? (6)
- Severe respiratory distress
- Petechial rash
- Subconjunctival hemorrhage
- Tachycardia
- Tachypnea
- Fever
How do you confirm diagnosis of fat embolism?
- presence of fat droplets in urine OR
2. Presence of intraarterial fat globules on fundoscopy
when do fat embolisms usually occur after fracture of long bone?
12-72 hours
what is hamman sign?
crunching sound on auscultation of the heart due to mediastinal emphysema
how do you treat complicated diverticulitis with abscess formation?
percutaneous abscess drainage under CT guidance
define and list the triad of leriche syndrome?
(arterial occlusion at the bifurcation of the aorta into the common iliac arteries)
- bilateral hip, thigh and buttock claudication
- impotence
- symmetric atrophy of the bilateral lower extremities due to chronic ischemia
what nerve is responsible for knee extension and hip flexion?
femoral nerve!
what nerve is at risk for injury in an anterior dislocation of the humeral head?
axillary
what is and how do you manage a hydrocele?
a fluid collection within the processus or tunica vaginalis
- management = reassurance and observation, most spontaneously resolve by the age of 12months
CXR shows widened mediastinum, large left sided hemothorax, deviation of the mediastinum to the R and disruption of the normal aortic contour
aortic injury secondary to rapid deceleration of the chest
varicocele is dilation of what veins? pathophys?
dilatation of pampiniform plexus
- incompetence of valves of these veins
- occurs most frequently on the left side
what are the criteria for SIRS?
- Temp greater than 38.5C (101.3F) OR less than 35C (95F)
- Pulse greater than 90
- Respirations greater than 20
- WBC >12,000 OR >10% bands OR <4,000
must have two of the 4 criteria
when is SIRS considered severe?
when there is end organ damage: 1 Oliguria 2. Hypotension 3. Thrombocytopenia (plt <80,000) 4. Metabolic acidosis 5. Hypoxemia
what does SIRS look like in a burn pt?
also have a hypermetabolic response:
- Hyperglycemia
- Muscle wasting
- Protein loss
- Hyperthermia
- Increased energy expediture
what is the greatest danger in massive hemoptysis?
Asphyxiation due to the airway flooding with blood
what is ludwig angina?
rapidly progressive bilateral cellulitis of the submandibular and sublingual spaces
- comes from infected 2nd or 3rd mandibular molar
presenting symptoms of Ludwig angina? (4)
- Fever
- Dysphagia
- Odynophagia
- Drooling
management of fracture of the scaphoid bone?
wrist immobilization for 6-10 weeks
young individual with a fleshy immobile mass on the midline hard palate
torus palatinus
surgically remove if symptomatic
what is vanishing bile duct syndrome?
primary biliary cirrhosis: rare disease involving progressive destruction of the intrahepatic bile ducts
what is the hallmark of primary biliary cirrhosis?
ductopenia (most common cause of it) other causes of ductopenia include failed liver transplant, hodgkins, sarcoid, CMV infxn, HIV and medication toxicity
how does one manage small nonbleeding esophageal varices?
prophylaxis with nonselective beta blockers (nadolol or propanolol)
how does one manage BLEEDING esophageal varices?
endoscopic sclerotherapy?
what medication is used for actively bleeding esophageal varices?? mechanism?
Octreotide: analog of simvastatin
causes splanchnic vasoconstriction and reduced portal blood flow by inhibiting the release of glucagon
what should you be highly suspicious of in a pt with hx of chronic cirrhosis with ascites who develops abdominal discomfort or altered mental status?
Spontaneous bacterial peritonitis
what are 6 classes of drugs that can cause pancreatitis?
- Diuretics: furosemide, thiazides
- Drugs for IBD: sulfasalazine, 5-ASA
- Immunosuppressive agents: azathioprine, L-asparaginase
- Dugs used by pt w hx of seizure or bipolar: valproic acid
- Dugs used by AIDS pts: didanosine, pentamidine
- Antibiotics: metronidazole, tetracycline
what type of bilirubin is excreted in the urine?
conjugated (bc its water soluble and only loosely bound to albumin)
What is rotor syndrome?
- benign condition in which there is a defect in hepatic storage of conjugated bilirubin
- increased conj bili on plasma and excreted in urine
- LFTs are normal
- no tx
what is the major cause of chronic diarrhea in HIV-infected patients with CD4 counts less than 180?
Cryptosporidium parvum
what anitbody do you see in primary biliary cirrhosis?
anti-mitochondrial
what is the tx of choice for primary biliary cirrhosis?
usodeoxycholic acid
what viruses are associated with acute pancreatitis? (6)
- Mumps
- Hepatitis B
- HIV
- Coxsackievirus
- CMV
- HSV
painless jaundice in a pt with conjugated hyperbilirubinemia and markedly elevated alk phosph
think intraabdominal malignancy obstructing biliary system (order a CT to confirm dx)
what are two history clinical clues that are characteristic of esophageal dysmotility seen in scleroderma?
- Sticking sensation in throat
2. dysphagia + heartburn
what are the two manometric findings in scleroderma esophageal dysmotility?
- Absence of peristaltic waves in the lower 2/3 of the esophagus
- Significant decrease in the lower esophageal sphincter tone
What are 3 drugs that can cause SIADH?
- Cyclophosphamide
- Carbamazepine
- SSRIs like fluoxetine
angiodysplasia is often seen in what two patient populations?
- Underlying aortic stenosis
2. End stage renal disease
PAS-positive material in the lamina propria of the small intestine
Whipple;s disease: t whippelii