General Surgery Flashcards

1
Q

What is the definition of a hernia?

A

Protrusion of viscera through it’s covering to an abnormal location

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2
Q

What is the definition of an emboli?

A

Solid or gas which has been carried in the bloodstream to a location different to its origin

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3
Q

What is the function of the ilioinguinal nerve?

A

Sensory supply of upper anteromedial thigh

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4
Q

What is the function of the genitofemoral nerve?

A

Sensory innervation of the upper thigh (anterior scrotum, mons pubis and labia majora)

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5
Q

What are things to look for on inspection during a DRE examination?

A
Skin tags
Pilonidal sinus
Abscess
Anal warts
Fissures
Fistulas
Excoriation 
External haemorrhoids
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6
Q

What are four potential causes of a right iliac fossa mass?

A

Caecal carcinoma, appendix abscess, Crohn’s disease, ovarian tumour/cyst

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7
Q

What would be the first investigation if you are considering an oesophageal carcinoma?

A

Uppper gastro-intestinal endoscopy

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8
Q

Manometry can be used to diagnose what condition which causes dysphagia?

A

Achalasia

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9
Q

What would achalasia look like on a barium swallow?

A

‘Bird’s beak’ appearance with a smooth tapering distally and possible oesophageal dilation above the lesion

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10
Q

How would a peptic stricture appear on barium swallow?

A

As a short pinch point (small area of narrowing)

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11
Q

How would oesophageal spasm appear on barium swallow?

A

One or more smooth areas of contraction in the oesophagus

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12
Q

What three investigations are used in staging oesophageal carcinoma?

A

Endoscopic ultrasound, PET scan, CT chest, abdomen and pelvis

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13
Q

Where are metastatic lesions likely to spread in oesophageal malignancy?

A

Liver and lung

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14
Q

What can commonly cause free intra-peritoneal air?

A

Perforated duodenal ulcer, perforated diverticulum, laparotomy 24 hours ago

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15
Q

Perforation of what structures cause gas to accumulate in the retroperitoneum?

A

Ascending colon, descending colon, 3rd part of the duodenum

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16
Q

What initial management is used for a volvulus of the sigmois colon?

A

Sigmoidoscopy and passage of decompressing flatus tube

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17
Q

What surgery may be required for recurrent sigmoid volulus?

A

Sigmoid colectomy

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18
Q

What causes a sigmois volulus?

A

Twisting of the bowel on lax mesentery

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19
Q

Which patients are more commonly affected by sigmoid volvulus?

A

Elderly or psychiatric patients

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20
Q

What percentage of colonic obstructions are from sigmoid volvulus?

A

1-2%

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21
Q

What are the six criteria for acute severe colitis established by Truelove and Witts?

A
  1. Frequency of stool >6 daily
  2. Overtly bloody stool
  3. Fever (>37.5)
  4. Tachycardia (>90)
  5. Anaemia (Hb<105)
  6. Raised ESR (>30)
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22
Q

In acute severe disease of UC why would a sigmoidoscopy be used over colonoscopy?

A

Colonoscopy increases risk of perforation

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23
Q

Why would you give heparin to a patient with acute severe colitis, what would make you not give it?

A

Patients with acute severe colitis are at high risk of thromboembolic events
Would give unless there is a significant haemorrhage

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24
Q

What medication is used in treatment of acute severe colitis?

A

Intravenous hydrocortisone 100mg every 6 hours
Bone protection from high steroids
Heparin as prophylactic

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25
Q

Why do patinets with long-standing ulcerative colitis need surveillance colonoscopies?

A

They are at increased risk of colonic carcinoma and need to be screened regularly with colonoscopy

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26
Q

What is thumbprinting on abdominal X-ray?

A

Radiographic sign of large bowel wall thickening from oedema or inflammation, the normal haustra become tickened appearing like thumbprint projections into lumen

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27
Q

What conditions are associated with toxic megacolon?

A

UC, Crohn’s, infective colitis

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28
Q

What is included in the standard trauma X-ray series?

A

Chest X-ray, lateral cervical spine, X-ray pelvis

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29
Q

What imaging modality is best for detection of splenic injuries?

A

CT

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30
Q

What is the most commonly injured solid organ in the abdomen?

A

The spleen

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31
Q

What precautions would you advice a patient about following splenectomy?

A

Vaccination (pneumococcal, meningococcal, haemophilus influenzae), long term penicillin V prophylaxis, caution with travel to areas of endemic malaria

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32
Q

Is achlasia associted with oesophageal malignancy?

A

Yes

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33
Q

What is achalasia?

A

Disease due to failure of normal peristalsis and relaxation of the lower oesophgeal sphincter

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34
Q

What tropical disease may cause similar clinical and imaging appearances to achalasia?

A

Chaga’s disease (trypanosomiasis)

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35
Q

Can achalasia cause painful dysphagia?

A

Yes

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36
Q

Can achalasia cause aspiration pneumonia?

A

Yes

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37
Q

What are treatments frequently used for achalasia?

A

Balloon dilatation, botox injections, Heller’s myotomy

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38
Q

What are the different types of gallstones?

A

Cholesterol stones, pigment stones, mixed stones

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39
Q

Haemolytic anaemia is associated with which type of gallstone?

A

Pigment

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40
Q

Which two ducts come together to form the common bile duct?

A

The cystic duct and common hepatic duct

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41
Q

What are common risk factors for gallstone disease? (The 5 Fs)

A
Fat
Female
Fertile (being pregnant)
Forty (peak age for women to present)
Family history
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42
Q

What causes biliary colic?

A

Impaction of gallbladder neck by a gallstone, there is no inflammation but pain on contraction of gallbladder

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43
Q

Why do patients often experience biliary colic after a fatty meal?

A

Fatty acids stimulate the duodenum endocrine cells to produce CCK which stimulates the gallbladder to contract

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44
Q

How does pain usually differ between biliary colic and acute cholecystitis?

A

Biliary colic: sudden, dull, colicky

Acute cholecystitis: constant

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45
Q

What is a positive Murphy’s sign?

A

Whilst applying pressure to the RUQ, ask the patient to inspire. There will be a halt in inspiration due to pain with a positive test

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46
Q

What can a positive Murphy sign indicate?

A

An inflamed gallbladder

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47
Q

What are three things to look for on abdominal ultrasound when suspecting gallstone disease?

A

Gallbladder wall thickening, presence of gallstones/sludge, bile duct dilatation

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48
Q

What is charcot’s triad?

A

Jaundice, fever and RUQ pain

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49
Q

What is Reynold’s pentad?

A

Jaundice, fever, RUQ pain, hypotension, confusion

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50
Q

What is Alvarado scoring system used to help diagnose?

A

Appendicitis

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51
Q

What are some categories in alavadro scoring system?

A

Pain moving to RIF, anorexia, N+V, RIF tenderness, fever, raised WCC

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52
Q

Which out of biliary colic, acute cholecystitis and cholangitis will caise jaundice?

A

Cholangitis

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53
Q

What is often observed on ultrasound when cholangitis is present?

A

Common bile duct dilatation

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54
Q

What is the most common cause of cholangitis?

A

Gallstones- blocking biliary tract

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55
Q

Following an open appendectomy would you be concerned if there was free air beneath the diaphragm?

A

This is a normal finding after surgery

56
Q

What are the 4HTs for reversible causes of cardiac arrest?

A

Hypovolaemia, hypo/hyperkalaemia, hypothermia, hypoxia

Toxins, cardiac Tamponade, Thrombus, Tension pneumothorax

57
Q

What are indications for dialysis in patient with AKI using mneumonic AEIOU?

A
Acidosis
Electrolytes
Intoxications
Overload
Uraemia
58
Q

What causes the majority of acute pancreatitis cases?

A

Gallstones and excess alchol consumption

59
Q

What are causes of pancreatitis? (GET SMASHED)

A
G-gallstones
E- ethanol
T- trauma
S- steroids
M- mumps
A- autoimmune
S- scorpion sting
H- hypercalcaemia 
E- ERCP
D- drugs (e.g azathioprine, NSAIDs, diuretics)
60
Q

What is pancreatitis?

A

Inflammation of the pancreas

61
Q

What is the pathophysiology of acute pancreatitis?

A

Digestive enzymes are activated within the pancreas resulting in an inflammatory response

62
Q

How does fat necrosis occur in acute pancreatitis?

A

Enzymes released from the pancreas into ystemic circulation causing autodigestion of fats which results in fat necrosis

63
Q

Why can you get hameorrhage in retroperitoneal space with acute pancreatitis?

A

Enzymes released from pancreas into systemic circultion autodigest blood vessels

64
Q

How do patients typically present with acute pancreatitis?

A

Severe epigastric pain which can radiate to the back, with nausea and vomiting

65
Q

What do Cullen’s and Grey Turner’s signs suggest?

A

Retroperitoneal haemorrhage

66
Q

Where does bruising occur with Cullen’s and Grey Turner’s signs?

A

Cullen’s: peri umbilical

Grey Turner’s: the flanks

67
Q

What are some causes of abdominal pain which radiates to the back?

A

AAA, renal calculi, chronic pancreatitis, aortic dissection, peptic ulcer disease

68
Q

Do serum amylase levels directly correlate with acute pancreatitis disease severity?

A

No

69
Q

What intial labatory test would you consider for acute pancreatitis?

A

Serum amylase, LFTs, serum lipase (if available at the hospital)

70
Q

What is the management of acute pancreatits?

A

IV fluid resuscitation, analgesia, NG tube if vomiting profusely, encourage oral intake as soon as tolerated

71
Q

What level of serum amylase is diagnostic of acute pancreatitis?

A

3 times the normal upper limit

72
Q

What is a pancreatic pseudocyst?

A

A collection of fluid containg pancreatic enzymes, blood and necrotic tissue, forming typically a few weeks post acute pancreatitis episode

73
Q

What surgery may be required for pancreatic necrosis?

A

Necrosectomy

74
Q

What is an adhesion?

A

Fibrous tissue that binds two surfaces of the body which are usually separate

75
Q

What is a fistula?

A

An abnormal connection between two epithelial surfaces

76
Q

What is tenesmus?

A

The sensation of needing to open bowels without being able to produce stools

77
Q

What happens in a hemicolectomy?

A

Removal of a portion of the colon

78
Q

What is a Hartmann’s procedure?

A

Proctosigmoidectomy- removal of the rectosigmoid colon with closure of the anorectal stump and formation of a colostomy

79
Q

What is an anterior resection in general surgery?

A

Removal of the rectum

80
Q

What is a Whipple procedure?

A

Pancreaticoduodenectomy- removal of the head of the pancreas, duodenum, gallbladder and bile duct

81
Q

What type of diathermy would you use for surgery on a patient with a pacemaker?

A

Bipolar diathermy

82
Q

What is the ASA grading system?

A

ASA grading system classifies physical status of the patient for anaesthesia from 1 (normal healthy) to 6 (brain-dead undergoing organ donation)

83
Q

Where is the most common area of duodenal ulceration?

A

The cap (first section) which ascends superiorly from pylorus of stomach

84
Q

How are the different sections of the duodenum categorised?

A

D1- superior
D2- descending
D3- inferior
D4 ascending

85
Q

What are the two most common causes of duodenal ulcers?

A

H. Pylori infection and chronic NSAID therapy

86
Q

What are some ways to reduce post op ileus?

A

Limit bowel handling and opiate use
Mobilise ASAP
Avoid fluid overload (bowel oedema)

87
Q

Extensive small bowel resections for Crohn’s disease can lead to what syndrome?

A

Short bowel syndrome

88
Q

What is a Hartmann’s procedure?

A

Complete resection of the rectum and sigmoid colon with the formation of an end colostomy and closure of rectal stump

89
Q

How should abdominal wound dehiscence initially be managed?

A

Cover wound with saline-soaked gauze and give Iv broad-spectrum antibiotics

90
Q

What is wound dehiscence?

A

When a surgical wound reopens

91
Q

What is the management of anal fissure?

A

(1st line) GTN ointment or diltiazem cream applied topically
Botulinum toxin
Then internal sphincterotomy if fail to respond to others

92
Q

What are some typical spinal features seen in ankylosing spondylitis?

A

Loss of lumbar lordosis and progressive kyphosis of cervical-thoracic spine

93
Q

What are the 3 categories of spina bifida?

A

Myelomeningocoele, spina bifida occulta and meningocoele

94
Q

What are features of anal fissures?

A

Painful, bright red rectal bleeding

Most commonly on posterior midline (if in other location consider underlying cause)

95
Q

What are some general risk factors for VTE?

A

Cancer/chemo, over 60, high BMI, dehydration, clotting disorder, HRT or COCP, pregnant, varicose veins, significant medical comorbidity

96
Q

What are two types of mechanical VTE prophylaxis?

A

Compression stockings

Intermittent pneumatic compression device

97
Q

What are some pharmacological options for VTE prophylaxis?

A

Low molecular weight heparin (e.g enoxiparin)
Unfractionated heparin
Fondaparinux sodium

98
Q

How long would you advice women to stop their COCP before surgery?

A

4 weeks before surgery

99
Q

What test is helpful to assess the exocrine function in chronic pancreatitis?

A

Faecal elastase

100
Q

Patients with a cholangiocarcinoma may have a raise in which tumour marker?

A

CA 19-9

101
Q

Levels of what enzyme are best for investigating suspected acute pancreatitis of a late presentation >24 hours

A

Serum lipase (has a longer half life than amylase)

102
Q

Where are diverticula most commonly found in the bowel?

A

Sigmoid colon

103
Q

What are the four different disease manifestations of diverticulum?

A

Diverticulosis, diverticular disease, diverticulitis, diverticular bleed

104
Q

What is diverticulitis?

A

Inflammation of a diverticula from bacterial overgrowth within the outpouching

105
Q

What is a diverticular bleed?

A

When a diverticula erodes into a vessel and causes a large volume painless bleed

106
Q

What are some risk factors for the formation of diverticula?

A

Low fibre diet, smoking, obesity, family history, NSAID use

107
Q

What are some clinical features of diverticular disease?

A

Intermittent lower abdo pain (typically colicky and relieved by defecation)
May also have associated change in bowel habit, nausea and flatulence

108
Q

What drugs that a patient may be taking can mask symptoms of diverticulitis?

A

Corticosteroids or immunosuppressants

109
Q

What is obturator sign when looking for appendicitis?

A

Pain with right knee flexed and right hip rotated internally
Positive sign indicates potential appendicitis

110
Q

What is psoas sign when looking for appendicitis?

A

Pain on extension of the hip (if retrocaecal appendix)

111
Q

What investigation would you request to rule out a post-operative intra-abdominal collection?

A

CT

112
Q

What size would a diverticular/pericolic abscess need to be for you to consider radiological drainage over IV antibiotics?

A

5cm

113
Q

What are some findings on CT that may been seen with diverticulitis?

A

Thickening of colonic wall, pericolonic fat stranding, abscesses, free air

114
Q

Would you do a colonoscopy for a presenting case of suspected diverticulitis?

A

No because of the risk of perforation

115
Q

How would you manage a patient with uncomplicated diverticular disease?

A

Simple analgesia, encourage oral fluid intake

116
Q

If a diverticular bleed fails to respond to conservative management, what are the surgical options?

A

Embolisation, surgical resection

117
Q

How would you manage acute diverticulitis conservatively?

A

Fluids, antibiotics, analgesia- should improve in a few days

118
Q

What surgical procedure may be required in diverticulitis patients with perforation with faecal peritonitis or overwhelming sepsis?

A

Hartmann’s procedure: sigmoid colectomy with formation of end colostomy

119
Q

How may a colovesical fistula present?

A

Recurrent UTIs, pneumoturia, or faecal matter in urine

120
Q

What are the most common complications of diverticular disease?

A

Strictures and fistula formation

121
Q

What is a peptic ulcer?

A

a break in the lining of the GI tract extending to the muscularis mucosae

122
Q

Where are peptic ulcers most likely to occur?

A

The lesser curvature of the stomach and 1st part of duodenum

123
Q

How does H-pylori infection lead to peptic ulcer disease?

A

Induces release of histamine which cause parietal cells to produce more acid
Down-regulates bicarbonate production

124
Q

What symptoms may a patient have with peptic ulcer disease?

A

Epigastric/retrosternal pain, nausea, bloating, post-prandial discomfort, early satiety

125
Q

With regards to eating when is the pain worse for gastric ulcers and duodenal ulcers?

A

Pain from gastric ulcers exacerbate by eating

Pain from duodenal ulcers are worse 2-4 hours after eating or are alleviated by eating

126
Q

When would you consider an urgent referral for upper oesophageal-gastro-duodenoscopy?

A

New-onset dysphagia
>55 with weight loss and abdo pain/reflux/dyspepsia
New onset dyspepsia not responding to PPI

127
Q

What is Zollinger-Ellison syndrome?

A

A triad of severe peptic ulcer disease, gastric acid hypersecretion, gastrinoma

128
Q

What is the characteristic finding in Zollinger-Ellison syndrome?

A

Fasting gastrin of >1000 pg/ml

129
Q

What should patients do about their current medication before a H.Pylori test?

A

Stop any current medical therapy for their symptoms 2 weeks prior to investigation

130
Q

What lifestyle advice would you give a patient with peptic ulcer disease?

A

Smoking cessation, reduce alcohol intake, weight loss, avoid NSAIDs

131
Q

What medication would we give a patient with peptic ulcer disease (not caused by H.Pylori)?

A

PPI e.g omeprazole

132
Q

What is the triple therapy we use for H.pylori infection?

A

PPI with oral amoxicillin and clarithromycin/metronidazole for 7 days

133
Q

What is the most common organism to cause cholangitis?

A

E Coli

134
Q

Where is McBurney’s point?

A

Two thirds of the way from the umbilicus to the ASIS

135
Q

What is the howship-Romberg sign and what pathology is this specific to?

A

Pain extending from the inner thigh to the knee when the hip is internally rotated.
This is due to compression of the obturator nerve e.g obturator hernia