General Medication SE and mchanism Flashcards
1
Q
Triptane contraindications
A
coronary artery disease non controlled hypertension SSRI MAO TCA Raynaud Pregancy Liver or Kidney disease below 18 and above 65
2
Q
Glucuronidation
A
Morphine Oxazepam Acetaminiphen CBZ Lamotrigine (VPA and Sertraline inhibit glucorination) Zidovudine
3
Q
Antiepileptic Protein binding
A
CBZ 85%
PYT 90%
VPA 90%
Phenobarbital 60%
Lamotrigine 55%
Primidone 35%
Topamax 15%
Keppra 10%
Ethosuximide 0%
4
Q
Hypercalcemia
A
anorexia nausea vomiting headache coma confusion Anxiety MYOCLONUS HIGH CSF PROTEIN
5
Q
Hypocalcemia
A
Increased ICP Come Depression Dementia Paraestheisa tetany SEIZURE
6
Q
Hypomagnesemia
A
Tetany Convulsions Tremor Apathy Coma Commonly with Hypo kalemia and hypo calcemia
7
Q
Hypermagnesemia
A
Curare like effect: no reflexes
Areflexia
Paralysis
Dilated Pupils
8
Q
Blocked ACTH release
A
Botulism
Lambert Eaton
Tick Paralysis Neurotoxin
Sea Snales Beta Neurotoxin
9
Q
Dagibatran Pradaxa
A
no reversal direct thrombin inhibitor GI Bleed more than coumadin RELY: GI and DYSPEPSIA CI: renal impairment, prosthetic heart valves, CBZ, PHT, Ketoconazole, cyclosporine
10
Q
Xarelto Rivaroxaban
A
8-12h direct factor X inh no reversal nonvalvular AF and DVT and PE RECORD AND ROCKET
11
Q
Apixaban
A
direct factor X
