General Knowledge On Iv Anaesthetic

Question 1

properties of an ideal iv anaesthetic

Answer 1

rapid onset
rapid recovery
analgesia at subanesthetic conc
minimal CV and resp depression
no emergence phenomena 
no pain on inj
no venous sequelae
safe if inadvertently injected into arteries
no release of histamine
water soluble solution
long shelf life
no stimulation of porphyria

Question 2

which one does not potentiate GABA

Answer 2

ketamin

Question 3

GABA fxn

Answer 3

inhibit CNS neurotransmission

Question 4

Ketamine and N2O has it effect at?

Answer 4

NMDA receptors

Question 5

classifications of iv anaesthetic

Answer 5

barbiturate
benzodiazepines
imazoles
phynols
phencyclidine

Question 6

factors affecting rate of transfer of iv anaesthetic on the brain and its effect

Answer 6

protein binding
blood flow to the brain extracellur pH and PKa of the drug
solubilities of the drug
speed of inj