General knowledge

Question 1

Common drugs that are enzyme inducers?

Answer 1

Phenytoin

Carbamazepine

Barbituates

Rifampicin

Alcohol

Sulphonylureas

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Inducers cause a decrease in drug concentration and activity

“PC BRAS”

Question 2

Common drugs that are enzyme inhibitors?

Answer 2

Allopurinol

Omeprazole

Disulfiram

Erythromycin

Valproate

Isoniazid

Ciprofloxacin

Ethanol (Acute intoxication)

Sulphonamides

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“AODEVICES”

Inhibitors reduce enzyme activity and cause an increase in drug concentrations and effects

“AODEVICES”

Question 3

Drugs to stop before surgery?

Answer 3

Insulin

Lithium

Anticoagulants/antiplatelets

COCP/HRT

K sparing diuretics

Oral hypoglycaemics

Perindopril (And other ACE inhibitors)

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“I LACK OP”