General knowledge

Question 1

Clinically significant anitbodies

Answer 1

IgGs (Rh, Kell, Kidd, Duffy, MNS) - cause hemolysis & HDFN

Question 1

Most immunogenic blood groups

Answer 1

Rh and Kell
- cause severe Transfusion rxns & HDFN

Question 2

Antibodies disappear and reappear AFTER transfusion

Answer 2

Kidd (Jk) “DHTR”

Question 3

Blood groups that are Cold Agglutinins

Answer 3

Anti-I (M. pneumoniae) and Anti-P (PCH)

Question 4

Needed for Rh-negative patients to prevent sensitization

Answer 4

Weak D Testing

Question 5

Enzymes DESTROY ___ & ___ but ENHANCE ___ & ___ reactions

Answer 5

Duffy & MNS, Kidd & Rh

Question 6

always screen for ___ BEFORE transfusion

Answer 6

Alloantibodies

Question 7

presents UNEXPLAINED anemia post-transfusion

Answer 7

Kidd (DHTR)

Question 8

Give Rh-negative mothers RhIg (RhoGAM) at __ weeks

Answer 8

28

Question 9

Monitor Kell-positive pregnancies with _____ for fetal anemia

Answer 9

Doppler Ultrasound (MCV-PSV)

Question 10

Duffy-negative (Fy[a–b–]) = _______

Answer 10

P. vivax resistance

Question 11

Risk of aplastic crisis in sickle cell patients

Answer 11

P

Question 12

Parvovirus b19 RECEPTOR

Answer 12

P

Question 13

Anti-_=M. pneumoniae
Anti-_=EBV

Answer 13

I, i

Question 14

Linked to CGD

Answer 14

chronic granulomatous disease

Kell

Question 15

____ syndrome = kell

Answer 15

McLeod

Question 16

complement receptor dysfunction; risk for autoimmune diseases

Answer 16

knops

Question 17

PNH

Answer 17

cromer

Question 18

Loss of CD55 (Decay-accelerating factor) = _____-mediated hemolysis in blood group ___

Answer 18

complement, cromer

Question 19

Groups with linked complement disorders

Answer 19

Knops & cromer