General info on chromosomes and mitosis Flashcards

1
Q

name of long arm on a chromosome

A

q

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2
Q

what is the nucleoid

A

central region without a membrane where DNA is stored in prokaryote (only eukaryotes have a nucleus)

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3
Q

where is the centromere

A

at the middle of chromosome, links all 4 legs together

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4
Q

define a chromosome

A

highly organized and compacted chromatin

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5
Q

what is the haploid number

A

number of different chromosomes

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6
Q

tip of the chromosome

A

telomere

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7
Q

how many chromatids are in a single straded chromosome

A

0; chromatids are only in ds chromosomes

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8
Q

definition and examples of ploidy levels

A

number of homologous chromosomes

ex; haploid (n) diploid (n)

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9
Q

name of short arm on a chromosome

A

p

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10
Q

what is the genome

A

all the genes of a cell

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11
Q

steps in cell cycle

A
interphase = G1, S, G2
mitotic phase (mitosis)
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12
Q

what are homologous chromosomes

A

same size, same shape, same genes

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13
Q

steps of mitosis

A

prophase, prometaphase, metaphase, anaphase, telophase

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14
Q

what is translocation

A

there is an extra piece of chromosome

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15
Q

what happens in G2

A

preparation for mitosis, growth (right after DNA replication)

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16
Q

what is cytokinesis

A

division of cytoplasm (starts in early anaphase and ends after telophase)

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17
Q

what does g stand for in G1 and G2

A

growth or gap

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18
Q

how are anomalies notated

A

2n + 1 (trisomy), this is a 2n organism with 1 extra chromosome

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19
Q

when does cytokinesis occur in animal cells

A

is starts at anaphase and ends after telophase

20
Q

How does mitosis work for prokaryotes?

A

there is no mitosis, it is binary fission

21
Q

What happens in G1?

A

cell growth, size increase, gene expansion (protein synthesis)

22
Q

functions of cell division

A

growth: formation of new cells
repair: new cells replace old damaged cells
asexual reproduction
aging because limited divisions are possible

23
Q

what is the nucleolus

A

round body in nucleus that makes ribosomes

24
Q

what is the period with most cell activity

25
what kind of cells undergo mitosis
somatic cells (anything no reproductive`)
26
what is cancer
uncontrolled cell growth
27
what is S phase
synthesis, DNA is replicated ss become ds
28
what happens in prophase
DNA condenses, organisms and chromosomes appear (chromatin condenses), nucleolus disappears as well as nuclear membrane, spindle fibers appear
29
what does MPF initiate
M-phase promoting factor; | mitosis may begin
30
what happens in prometaphase
spindle fibers (made of microtubules) attach to chromosomes (to kinetochore which is attached to the centromere)
31
ploidy level of each phase of mitosis
all 2n except for anaphase when chromosomes are separated but nuclear membrane is not there yet
32
how many chromosomes in a human cell
23 pairs of homologous chromosomes (46 total)
33
what is SPF
s phase promoting factor
34
what happens in metaphase
chromosomes align
35
when does the nuclear membrane disappear
starts to disappear in prophase and ends in prometaphase
36
G1/S checkpoint (at end of G1)
stopping point in cell cycle: cell checks: for cell double in size, growth rate adequate presence on growth factors if cues present then SPF (s phase promoting factor) will be produced if not cell falls in G0 (just does its job, no division)
37
what happens in telophase
opposite of prophase: nuclear membrane reappears, nucleoli reappear, spindle fiber disappear
38
when does cytokinesis occur in plant cells
after mitosis; cell plate forms and this becomes cell wall
39
What is mitotic spindle check point
cell waits until all kinetochores are attached, is its okay APC activated
40
what happens once SPF is activated
start of s phase: | DNA replication occurs
41
what is APC
allows chromatids to separate, inactivates MPF: spindle breakdown chromosomes decondense (telophase)
42
when are spindle fibers present
they appear in prophase and disappear in telophase
43
G2/M check point after G2
another pause in cycle: check for: mass or growth rate or time and complete replication if check point completed MPF activated (metaphase promoting factor), mitosis may begin
44
What is the kinetichore
protein attached to centromere (one on each sister chromatid) that will connect to spindel fibers
45
what are centrosomes made of
2 centrioles (the 2 cylinders composed of microtubials)
46
When does cytokinesis start
early anaphase
47
When are organelles replicated
In G1 (before DNA is replicated; they don't want to replicate DNA for nothing, it is done last)