General health Flashcards

1
Q

What is the screening tool used in primary care to test for problem drinking and potential alcohol problems?

A

CAGE questionnaire.

> 2 or equal to 2 should prompt further exploration

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2
Q

Which questionnaire assesses for high risk alcohol use?

A

AUDIT

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3
Q

Which questionnaire assesses for the severity of alcohol dependence?

A

SADQ

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4
Q

What interventions are recommended for individuals with moderate to severe alcohol dependence, particularly when they have limited social support, complex comorbidities, or haven’t responded to initial community-based treatments?

A

Offer intensive structured community-based interventions.

Consider pharmacological interventions (e.g., acamprosate, oral naltrexone) administered by specialists.

Ensure psychological interventions are based on evidence-based treatment manuals.

Staff should receive regular supervision, use outcome measurements, and monitor treatment adherence.

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5
Q

In the context of alcohol dependence, what considerations should be taken into account when assessing individuals who typically consume over 15 units per day, and what interventions may be offered based on the assessment outcome?

A

Consider offering an assessment for community-based assisted withdrawal.

If safety concerns arise, consider assessment and management in specialist alcohol services.

For successful withdrawal, consider offering acamprosate or oral naltrexone with individual psychological interventions.

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6
Q

What are the criteria for considering inpatient or residential assisted withdrawl in individuals with alcohol dependence?

A

Consider inpatient withdrawal for those drinking over 30 units per day, scoring over 30 on the SADQ, or having specific medical conditions.

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7
Q

What drug regimens are recommended for assisted withdrawal in community-based programs for mild to moderate alcohol dependence?

A

Offer outpatient programs with fixed-dose benzodiazepines, averaging 2-4 meetings per week for the first week.

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8
Q

What is the preferred medication for assisted withdrawal in individuals with alcohol dependence, and how should it be prescribed and monitored?

A

Prefer benzodiazepines (chlordiazepoxide or diazepam) in fixed-dose regimens, prescribing for instalment dispensing. Monitor users every other day during assisted withdrawal.

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9
Q

When managing withdrawal from co-existing benzodiazepine and alcohol dependence, what is the recommended approach and duration of withdrawal regimens?

A

Manage withdrawal with one benzodiazepine and inpatient regiments should last 2-3 weeks or longer, tailored to the severity and circumstances of the individual.

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10
Q

What are the treatment goal differences for individuals with alcohol misuse in specialist alcohol services?

A

Abstinence is recommended for dependence

Moderation may be considered for mild cases

Harm reduction is an option for those unwilling to aim for abstinence initially, with encouragement for eventual absitnence.

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11
Q

How should thiamine be managed for individuals at high risk of Wernicke’s encephalopathy, especially during assisted alcohol withdrawal in specialist settings, according to NICE guidelines?

A

For those at risk in specialist inpatient or prison settings with malnutrition or decompensated liver disease, offer parenteral thiamine followed by oral thiamine. People with Wernicke-Korsakoff syndrome should be placed in supported living or 24-hour care, adapted for cognitive impairment, emphasizing abstinence support.

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12
Q

Can Varenicline or Bupropion be prescribed to pregnant or breastfeeding women or people under 18?

A

No

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13
Q

What withdrawal symptoms is a person likely to experience when they stop smoking?

A
  • Irritability
  • Frustration
  • Anger
  • Anxiety
  • Difficulty concentrating
  • Increased appetite
  • Restlessness
  • Depressed mood
  • Insomnia
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14
Q

What are the benefits of stopping smoking?

A
  • Stopping smoking before the age of 40 avoids over 90% of the increased risk of dying caused by continuing to smoke.
  • Circulation improves
  • Risk of heart attack, lung cancer reduces
  • Carbon monoxide is almost eliminated from the body.
  • Ability to taste and smell improves.
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15
Q

If a person smokes, what is included in VBA? (very brief advice)

A

VBA is typically given in less than 30 seconds:
* Ask about current and past smoking behaviour.
* Provide verbal and written information on the risks of smoking and the benefits of stopping smoking.
* Advise on the options for quitting smoking including behavioural support, medication and e-cigarettes.
* Refer the person to their local stop smoking service (if they wish to stop smoking).

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16
Q

What is the first step in a patient who wants to quit smoking?

A

Referral to the local NHS stop smoking services

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17
Q

What is involved in NHS stop smoking services?

A
  • Carbon monoxide measurement
  • If they want to be involved in a group they can or they can have 1-1
  • Patches, nicotine replacement given. Champix (tablets), can get from boots. Champix programme.
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18
Q

If a person does not want to stop smoking, what harm reduction methods might be used?

A

Stopping smoking, but continuing to use NRT.

Cutting down before stopping smoking, with or without NRT.

Smoking reduction, with or without NRT.

Temporary abstinence from smoking, with or without NRT.

NRT may be used as long as necessary to prevent relapse.

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19
Q

In pregnancy, what is the recommended option for smoking cessation, and how does it compare to using e-cigarettes?

A

For pregnant individuals, licensed nicotine replacement therapy (NRT) products such as patches and gum are recommended over e-cigarettes, as the safety of e-cigarette vapour for the baby is unknown.

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20
Q

What are e-cigarettes and how do they work?

A

An e-cigarette is a device that allows the inhalation of nicotine in vapor form without burning tobacco or producing tar and carbon monoxide. It works by heating an e-liquid containing nicotine, propylene glycol, vegetable glycerine, and flavorings.

21
Q
A
  • ## Discuss alcoholic support groups
22
Q

What should you safety net alcoholics about?

A

Hepatic encephalopathy

  • Agitation
  • Confusion
  • Disorientation
  • Muscle stiffness
  • Difficulty speaking
23
Q

What follow up should you arrange with alcoholics?

A
  • Exclude drug causes: statins, NSAIDs, herbal remedies, if no drug involvement repeat ALT and other LFTs in 2-3 months, advise abstinence from alcohol and weight loss, if ALT is still abnormal do the following investigations:

USS of liver

Hep B and C serology, lipids, ferritin and transferrin solution, autoimmune profile, immunoglobulins, coeliac, alpha 1 antitrypsin and ceruloplasmin if pt under 40.

If the result above are normal and ALT remains greater than 100U/L refer to GI medicine team and consider a liver biopsy

24
Q

What are the 4 Ls you can use when asking about consequences from alcohol use

A

Lover
Law
Livelihood
Liver

25
Q

Who is Disulfuram best for?

A

Disulfuram- best for people who want to drink in the evening

26
Q

Who should NOT stop drinking?

A

People who are dependent on alcohol- 100 of units, people that get bad withdrawal.

People with previous withdrawal- shaking

Should be referred under turning point in Leicester.

Reduce by half and not stop completely

27
Q

Why do you prescribe benzodiazepines in alcoholics?

A

Do reduce the risk of seizures

28
Q

What carbon monoxide level after 4 weeks suggests a patient is a non smoker?

A

4 weeks less than 10ppm
Now classed as a non smoker

29
Q

What is fournier’s gangrene?

A

Fournier gangrene is an acute necrotic infection of the scrotum, penis or perineum. It is characterized by scrotum pain and redness with rapid progression to gangrene and sloughing of tissue.

30
Q

Give three drugs used in alcohol cessation

A
  • Disulfaram (blocks the enzyme which breaks down acetaldehyde)
  • Naltrexone (opioid antagonsit)
  • Acamprosate (promoting a balance between the excitatory and inhibitory neurotransmitters, glutamate and gamma-aminobutyric acid)
31
Q

What are some useful contacts for alcohol/drug abuse in Leicester?

A
  • Turning point
  • Drinkline (national alcohol helpline)
  • Alcoholics Anonymous
  • Adfam
32
Q

What are some smoking cessation support services in Leicester?

A
  • Live well Leicester
  • Quit ready Leicestershire and Rutland
33
Q

How do smoking cessation clinics help with preventing relapse?

A
  • Advisers provide weekly support for 4 weeks, then less often for 8 weeks, to keep motivation high.
  • Stop smoking treatments
  • Understanding triggers
  • Have carbon monoxide levels tested
34
Q

What is harmful drinking (high-risk drinking) according to the guideline?

A

Harmful drinking is a pattern of alcohol consumption causing health problems directly related to alcohol.
Health problems can include psychological issues like depression, alcohol-related accidents, or physical illnesses such as acute pancreatitis.
Long-term consequences may include high blood pressure, cirrhosis, heart disease, and certain types of cancer.

35
Q

How is alcohol dependence characterized, and why is it important to assess its severity?

A

Alcohol dependence is characterized by craving, tolerance, preoccupation with alcohol, and continued drinking despite harmful consequences.
Severity assessment is important for guiding interventions.
Severity categories (mild, moderate, severe) are based on the Severity of Alcohol Dependence Questionnaire (SADQ) score.
Assessment helps determine the need for assisted alcohol withdrawal and the appropriate setting for management (community or inpatient).

36
Q

What challenges exist in the current management of alcohol misuse, according to the guideline?

A

Under-identification by healthcare professionals.
Limited availability of specialist alcohol treatment services.
Varied access to assisted withdrawal and treatment programs across regions.
Lack of structured community-based withdrawal programs.
Limited access to psychological interventions like cognitive-behavioral therapies.
Poorly developed service structures despite national guidance, leading to ill-defined care pathways.

37
Q

What is a brief intervention for alcohol misuse and what does it involve?

A

A brief intervention is a short counselling session lasting 5 to 10 minutes. It covers risks associated with drinking, advice on reducing alcohol intake, support networks, and addressing emotional issues related to drinking.

38
Q

What are the treatment options for alcohol misuse based on the extent of drinking and goals of the individual?

A

Treatment options depend on drinking patterns and goals. They include moderation or abstinence. Abstinence is strongly recommended for individuals with liver damage, other medical problems worsened by alcohol, those on specific medications, pregnant individuals, or those previously unsuccessful with moderation.

39
Q

What medications are recommended by NICE for treating alcohol misuse, and how do they work?

A

NICE recommends medications such as acamprosate, disulfiram, naltrexone, and nalmefene. Acamprosate and naltrexone help prevent relapse or limit alcohol consumption. Acamprosate affects GABA levels, reducing cravings, while naltrexone blocks opioid receptors, reducing alcohol’s effects.

40
Q

What medications are commonly used in alcohol detoxification, and how do they work?

A

Medications like chlordiazepoxide may be used to ease withdrawal symptoms during detoxification. Chlordiazepoxide helps to alleviate symptoms such as anxiety and tremors by acting on the brain’s GABA receptors.

41
Q

What are the potential withdrawal symptoms during alcohol detoxification, and how long do they typically last?

A

Withdrawal symptoms can include nausea, tremors, insomnia, and anxiety. These symptoms are typically most severe in the first 48 hours and may last 3 to 7 days, with sleep disturbances persisting for up to a month.

42
Q

What are some common therapies used in treating alcohol dependency, and how do they work?

A

Therapies such as cognitive-behavioral therapy (CBT), 12-step facilitation therapy, and family therapy are commonly used. CBT helps individuals identify and change unhelpful thoughts and behaviors related to alcohol, while family therapy supports both the individual and their family members in understanding and coping with alcohol dependency.

43
Q

What are two malignant diseases that obesity is a risk factor for?

A
  • Ovarian
  • Breast
  • Endometrial
  • Bowel cancer
44
Q

What are some conditions that can predispose to palpitations?

A
  • Metabolic syndrome
  • Obesity
  • Hypertension
  • Obstructive sleep apnoea
45
Q

What makes up the fraser guidelines?

A
  1. They have sufficient maturity and intelligence to understand the nature and implications of the proposed treatment
  2. They cannot be persuaded to tell their parents or to allow the doctor to tell them
  3. They are very likely to begin or continue having sexual intercourse with or without contraceptive treatment
  4. Their physical or mental health is likely to suffer unless they received the advice or treatment
  5. The advice is in their best interests
46
Q

Can Hepatitis A cause a chronic infection?

A

No only Hepatitis C and D cause a chronic infection

47
Q

What is normocytic anaemia associated with?

A

Normocytic anaemia is associated with malignancy, chronic disease, primary marrow disorders and haemoglobinopathies.

48
Q

What is the upper age limit for an abortion in the UK?

A

24 weeks

49
Q

What are the circumstances of doing an abortion older than 24 weeks?

A

They can be carried out after 24 weeks in very limited circumstances – for example, if the mother’s life is at risk or the child would be born with a severe disability.