Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Hematology > General First Aid/Boards > Flashcards

General First Aid/Boards Flashcards

1
Q

Component of RBC that allows it’s flexibility and biconcavity

A

Spectrin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

WBC Differential from highest to lowest

A

Neutrophils Like Making Everything Better

Neutrophils, Lymphocytes, Monocytes, Eosinophils, Basophils.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Causes of Eosinophilia

A

PANAC

Parasites (invasive), Asthma, Neoplasia, Allergic Processes, Chronic Adrenal Insufficiency.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Fetal Erythropoiesis: Locations

A

Young Liver Synthesizes Blood

Yolk Sac, Liver, Spleen, and Bone Marrow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Hemoglobin Development

A

Alpha Always, Gamma Goes, Becomes Beta: From Fetal to Adult hemoglobin.

Higher affinity for O2 in fetal hemoglobin.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Hemophilia Types + Deficiency

A
  • Hemophilia A = Factor 8 (A sounds like Eight), increase PTT
  • Hemophilia B = Factor 9 (B-Nine), increase PTT
  • Hemophilia C = Factor 11
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Vitamin K dependent (Hence inhibited by warfarin, warfarin enhances the activity of antithrombin)

A

DiSCo started in 1972
- Factor 10, 9, 7, 2 and Protein C and S
Note: Protein C and S inhibit Va and VIIIa (the coagulation accelerators)
Note: Factor 10 = Rate Limiting coagulation step.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Platelet (thrombocyte) receptors + products in contains

A 
GpIb = vWF receptor
GpIIb/IIIa = Fibrinogen receptor
  • Dense granules (ADP, Ca2+)
  • alpha granules (vWF, fibrinogen)

Note: Derived from megakaryocytes, life span of 8-10 days.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

General Hemolytic Drugs that inhibit…

  • TXA2
  • ADP induced expression of GpIIb/IIIa
  • GpIIb/IIIa directly
  • Gp1B via vWF act.
A
  • TXA2 = Aspirin
  • ADP induced expression of GpIIb/IIIa = Clopidogrel, prasugrel, and ticlopidine
  • GpIIb/IIIa directly = Abciximab, eptifibatide, and tirofiban
  • GpIB via vWF act. = Ristocetin
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Thrombogensis deficiencies and associated syndromes

  • vWF
  • GpIb
  • GpIIb/IIIa
A
  • vWF = Vol Willebrand disease
  • GpIb = Bernard Soulier Syndrome
  • GpIIb/IIIa = Glanzmann Thrombasthenia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Basophilic Stippling

A

Lead Poisoning

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Degmacyte (Bite Cell) + Heinz Bodies

A

G6PD deficiency

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Ringer sideroblast

A

Sideroblastic anemia, excess iron in mitochondria (lead poisoning)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Schistocyte

A

Helmet Cell, DIC, TTP/HUS, HELLP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Dacrocyte

A

“teardrop cell” = Bone marrow infiltration (caused by being mechanically squeezed out of it’s home in the bone marrow)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Target Cell

A

“HALT said the hunter to his target”

  • HbC disease
  • Asplenia
  • Liver Disease (also see acanthocyte “spur cell”)
  • Thalassemia
17
Q

Howell Jolly Bodies

A

Hyposplenia or Asplenia

Hematology (7 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions