General Embryology Flashcards
What makes up the first 8 weeks of gestation? (2)
Preimplantation and embryonic period
Each craniofacial structure has a….?
Primordium
After fertilization of the zygote mitosis leads to what?
Blastocyst
What structure implants into the uterus?
blastocyst
What is critical for craniofacial development?
BMP (Bone Morphogenic Protein)
HOX genes are the blue print for?
Develop limbs and spine
Msx Genes genes are the blue print for?
differentiation and proliferation
Shh (sonic hedgehog) genes are the blue print for?
induction of facial primordium
Dlx genes genes are the blue print for?
lateral border of the neural plate
What are Ca dependent adhesion molecules?
Cadherins
Neurectoderm progenitors express
N-CAM
Skin Ectoderm progen
L-CAM
After the zygote cleaves a few times it is called
morula
How long does a blastocyst endure for?
until 3 distinct germ layers have formed.
What things form during the embryonic period? (3)
Pharyngeal arches
Somite development
Face development
What occures during patterning in embryonic period?
spatial and temporal events
Gastrulation is what?
Formation of 3 germ layers
Dorsal cells are also known as?
epiblast layer
Ventral cells are also known as?
Hypoblast layer
Hypoblast and epiblast layers form from?
Germ Disk
What cells form the true embryonic endoderm and mesoderm?
mesoblast cells
what is the primitive mouth called in embryological development
stomodeum
What part of the mesoderm forms cartilage, segmented muscles?
Paraxial
What part of the mesoderm forms Kidneys, gonads?
Inetermediate
What part of the mesoderm forms Heart, GUt?
Lateral Plate
The neural tube expands to form what there parts?
Forebrain
Midbrain
Hindbrain
What is it called when the neural crest cells fail to migrate to the facial region?
Treacher Collins Syndrome
What causes the mesoderm to break apart?
attachment proteins from E to N
What 3 tings happen post gastrulation?
- ) Differentiation of nervous system
- ) Formation/migration of the neural crest
- ) Embryo folding
