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NAPLEX > General Drug Knowledge > Flashcards

General Drug Knowledge Flashcards

1
Q

Heparin dosing for pulmonary embolism

bolus & continuous infusion

A

80 units/kg bolus followed by 18 units/kg/hr until aPTT goal reached

aPTT goal:

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2
Q

What is the drug of choice for treatment of HIT?

HIT = heparin-induced thrombocytopenia

A

argatroban

drug class: direct thrombin inhibitor

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3
Q

What are the major side effects of inhaled beta-2 agonists?

(i.e. albuterol)

A
  • tremor
  • hyperglycemia
  • hypokalemia
  • nervousness
  • shakiness
  • cough
  • tachycardia
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4
Q
A
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5
Q

What is the reversal agent for dabigatran?

dabigatran (brand: Pradaxa)

A

idarucizumab (Praxbind)

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6
Q

What drug class is enoxaparin?

enoxaparin (brand: Lovenox)

A

low-molecular-weight heparin (LMWH)

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7
Q

What is theophylline’s MOA?

A

nonselective phosphodiesterase inhibitor that increases cAMP and ultimately leads to bronchodilation

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8
Q

What are the major side effects of inhaled beta-2 agonists?

(i.e. albuterol)

A

nervousness; tremor; tachycardia; cough; hyperglycemia; hypokalemia

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9
Q

Theophylline therapeutic range

A

5 - 15 mcg/ml (peak level)

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10
Q

Nitrofurantoin is contraindicated if CrCl < ____ ml/min.

A

Nitrofurantoin is contraindicated if CrCl < 60 ml/min.

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11
Q

Voriconazole cannot be administered IV to patients with CrCl < ____ ml/min.

A

Voriconazole cannot be administered IV to patients with CrCl < 50 ml/min.

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12
Q

TDF is contraindicated in patients with CrCl < ____ ml/min.

TDF = tenofovir disoproxil fumarate

A

TDF is contraindicated in patients with CrCl < 50 ml/min.

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13
Q

TAF is contraindicated in patients with CrCl < ____ ml/min.

TAF = tenofovir alafenamide

A

TAF is contraindicated in patients with CrCl < 30 ml/min.

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14
Q

NSAIDs are contraindicated in patients with CrCl < ____ ml/min.

A

NSAIDs are contraindicated in patients with CrCl < 30 ml/min.

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15
Q

Rivaroxaban is contraindicated in patients with CrCl < ____ ml/min.

rivaroxaban = xarelta

A

Rivaroxaban is contraindicated in patients with CrCl < 30 ml/min.

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16
Q

Dabigatran is contraindicated in patients with CrCl < ____ ml/min.

dabigatran = pradaxa

A

Dabigatran is contraindicated in patients with CrCl < 30 ml/min.

17
Q

SGLT2 inhibitors are contraindicated in patients with an eGFR < ____.

A

SGLT2 inhibitors are contraindicated in patients with an eGFR < 30.

18
Q

Metformin is contraindicated in patients with an eGFR < ____.

A

Metformin is contraindicated in patients with an eGFR < 30.

NAPLEX (6 decks)

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