General Bacteriology Flashcards
What are commensals?
Microorganisms living on or within humans that do not harm the host under normal circumstances and may even be beneficial
How can commensals be beneficial?
Inhibiting growth of pathogens
Aiding in digestion
Name normal skin flora
Staph epidermidis
Name normal nasal flora
Staph epidermidis
Name normal oropharyngeal flora
Viridans group strep
Name normal flora of dental plaques
Strep mutans
Name normal gut flora
E coli
Bacteroides
Name normal vaginal flora
Lactobacillus acidophilus
Name normal lung flora
Neisseria catarrhalis
Alpha hemolytic strep
Staph
Non-pathogenic corynebacteria
Candida albicans
What are transient flora and give examples
Microorganisms that are temporarily present
E coli or s aureus on the hands
How can pathogens be differentiated?
Facultative versus obligate pathogens
What are facultative pathogens?
Microorganisms capable of survival outside of a host
Give examples of facultative pathogens
E coli
Vibrio cholera
Pseudomonas aeruginosa
Give examples of opportunistic pathogens
Oral candida
PJP
CMV
Cryptococcus
Toxoplasma encephalitis
What are obligate pathogens?
Microorganisms that can only replicate inside the cells of a host and therefore must infect a host to survive
Give examples of obligate pathogens
Salmonella
T pallidum
Mycobacterium tuberculosis
Which fatty acid can be found in the cell walls of acid fast bacteria?
Mycolic acid
Which enzyme cross links peptide side chains?
Transpeptidase
What is peptidoglycan?
A polymer chain of the sugars, n-acteyl-muramic acid and n-acetyl-glucosamine, and amino acids
What does lipoteichoic acid stimulate the release of?
TNF-alpha
IL-1
IL-6
Which endotoxin does the outer membrane of gram negative bacteria contain?
Lipopolysaccharide (LPS)
What is LPS composed of?
Lipid A
Core polysaccharide
O antigen
Which component of LPS is antigenic?
Lipid A
What does lipid A stimulate the release of?
TNF-alpha
IL1
IL6