General and Ocular Pharma (pre-board 2019 practice) Flashcards

1
Q

which of the ff. does not belong to pharmacokinetics

  • bioavailability
  • biotransformation
  • pharmacologic effect
  • excretion
A

pharmacologic effect

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2
Q

it is a process whereby drugs or metabolites are irreversibly transferred from internal to external through renal or non renal route

A

excretion

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3
Q

important in determining both the duration of drug action and the rate of drug elimination

A

excretion

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4
Q

it is the fraction of administered drug that reaches the systemic circulation

A

bioavailability

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5
Q

as the chemical conversion of one form to another

A

biotransformation

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6
Q

biotransformation is also known as

A

metabolism

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7
Q

metabolism is also known as

A

biotransformation

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8
Q

T/F

Oral route of drug administration the safest route because…

wrong medication is not harmful if taken only once since only fraction of the drug is absorbed

A

T

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9
Q

T/F

Oral route of drug administration the safest route because…

may undergo extensive liver metabolism before it is distributed in the body

A

T

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10
Q

T/F

Oral route of drug administration the safest route because…

it has to undergoes first pass effect

A

T

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11
Q

put definition of active transport

A

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12
Q

put definition of simple diffusion

A

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13
Q

put definition of facilitated diffusion

A

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14
Q

put definition of phagocytosis

A

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15
Q

mechanism of absorption of lipid soluble drugs:

  • active transport
  • simple diffusion
  • facilitated diffusion
  • phagocytosis
A
  • simple diffusion
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16
Q

parenteral injection with an angle of 10 degree

A

intradermal

17
Q

parenteral injection with an angle of 90 degree

A

intramuscular

18
Q

parenteral injection with an angle of 45 degree

A

subcutaneous

19
Q

routes of drug administration that follows the first pass effect

  • sublingual
  • buccal
  • oral
  • intravenous
A

oral