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Head And Neck > General > Flashcards

General Flashcards

1
Q

What drug can be used with radical XRT in patients unfit for cisplatin?

A

Cetuximab

Bonner trial - cetuximab & XRt v XRT alone. OS 49m v 29m

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2
Q

What are the main SE of cetuximab?

A 
Hypersensitivity
Skin rash
Low Mg
Headache after C1
Transient hepatic enzyme elevation
Cough/dyspnoea
Conjunctivitis
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3
Q

What is the dose of cetuximab in the concurrent setting?

A

400mg/m2 loading (1week prior to XRT), then 250mg/m2 weekly

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Head And Neck (8 decks)

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