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RENAL PHARM...Diuretics > General > Flashcards

General Flashcards

1
Q

Diuretic

A

agent which produces increased urine flow rate

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2
Q

Natriuretic

A

agent which increases urinary sodium excretion

all are diuretics b/c increased solute excretion leads to increased water excretion

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3
Q

Acetazolamide

A

Diamox

C.A. Inhibitor

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4
Q

Mannitol

A

Osmotic Diuretic

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5
Q

Ferosemide

A

Lasix

Loop Diuretic

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6
Q

Torsemide

A

Demadex

Loop Diuretic

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7
Q

Bumetanide

A

Bumex

Loop Diuretic

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8
Q

Hydrochlorothiazide

A

Esirdrex

Works primarily in DCT

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9
Q

Metolazone

A

Zaraloxyn

Works primarily in DCT

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10
Q

Chlorthalidone

A

Hygroton

Works primarily in DCT

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11
Q

Quinethazone

A

hydromox

Works primarily in DCT

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12
Q

Spironolactone

A

aldactone

Works primarily in DCT

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13
Q

Eplenerone

A

inspra

Works primarily in DCT

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14
Q

Amiloride

A

midamor

Works primarily in DCT

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15
Q

Triamterene

A

dyrenium

Works primarily in DCT

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16
Q

Arginine vasopressin

A

Acts on collecting ducts by V2R agonism

17
Q

Desmopressin

A

ddavp

Acts on collecting ducts by V2R agonism

18
Q

Conivaptan

A

vaprisol

Acts on collecting ducts by V2R antagonism

19
Q

Tolvaptan

A

samsca

Acts on collecting ducts by V2R antagonism

20
Q

used in combo w/…

A

beta blockers…dec mortality in pts w/ HTN

21
Q

Diuretics and ACEIs are the best tolerated drugs for monotherapy of…

A

HTN

22
Q

More efficient diuretics than thiazides….used in pts w/ severe HTN unresponsive to thiazides, esp w/ renal insufficiency, cardiac failure, or cirrhosis

A

Loop diuretics

23
Q

resulting natriuresis w/ these agents can be excessive…more side effects than thaizides…require frequent monitoring

A

Loops

24
Q

Due to high efficacy, administered IV in HTN crisis or acute pulmonary edema

A

Loops (esp. Furosemide)

25
Q

Useful in pts w/ hyperuricemia

A

K-Sparing

26
Q

diuretic of choice in cirrhosis

A

Spironolactone

27
Q

Equipotent to thiazides as antihypertensives

A

K-sparing

28
Q

contraindicated in significant renal insufficiency (GFR <75)

A

K-Sparing

29
Q

Chronic Renal failure

A

loop diuretic

30
Q

Nephrotic syndrome

A

Loop

31
Q

Moderate of severe CHF

A

Loop

32
Q

Cirrhosis

A

Spironolactone

33
Q

Cirhosis w/ CrCl<50

A

Spironolactone + Loop

34
Q

Cirrhosis w/ CrCl>50

A

Spironolactone+Thaizide

35
Q

Mild CHF w/ CrCl<50

A

Loop

36
Q

Mild CHF w/ CrCl>50

A

Thiazide

or loop?

37
Q

Nephrogenic Diabetes Insipidus

A

Thiazides

RENAL PHARM...Diuretics (9 decks)

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