Atrial natriuretic peptides

Question 1

Atrial natriuretic peptides (ANP)

Answer 1

small peptides hormones released primarily by cardiac atria in response to increased atrial stretch (i.e. volume expansion)

Question 2

ANP MOA

Answer 2

binds to receptors in medullary CD and leads to increased intracellular cyclic GMP

Question 3

ANP results

Answer 3

Decreased Na reabsorption and thus increased solute excretion leads to increased water excretion
NO CHANGE in rate of K excretion!!!