General

Question 1

What are the two main (serious) side effects of statin drugs?

Answer 1

Rhabdomyolysis and acute drug induced hepatitis.

Question 2

what are some side effects of statin drugs (general)?

Answer 2

myalgia, fatigue, and elevated liver enzymes.

Question 3

What is rhabdomyolysis and what lab test do you do?

Answer 3

• Rhabdomyolysis is the breakdown of skeletal muscle. It can cause kidney damage.
• it can be associated with statin use.
• To assess, stop the statin and check a creative kinase (CK).

Question 4

Name some potent inhibitors (medications) of the CYP 450 system.

Answer 4

• macrolides (clarithromycin, pediazole)
• antifungals (ketoconazole, fluconazole)
• cimetidine (Tagamet)
• citaprolam (Celexa)
• cisapride (Propulsid, pulled from the U.S. Market)

Question 5

One of the most common drug-to-drug interactions seen in primary care is between what two medications?

Answer 5

Between Bactrim and warfarin (Coumadin).

- sulfa drugs increase the blood level of warfarin, which increases the INR and increases the risk of bleeding.

Question 6

What is one of typical complaints of a patient with cataracts?

Answer 6

• they report a sensitivity to light

- they may also be at a higher risk for falls.

Question 7

How long should a patient be treated with antibiotics if he has prostatic is due to a STI?

Answer 7

Longer than 14 days, up to 4-6 weeks. Treatment can be expensive.
- the prostate gland does not readily absorb the antibiotic and is resistant to treatment.

Question 8

What assessments should be made in the patient who reports a fall but is not seriously hurt?

Answer 8

• any recent medications, in the last few hours up to the last 72 hours.
• also evaluated blood pressure in a variety of positions, sitting, standing, supine

Question 9

Hematuria in men is commonly seen with what conditions?

And not with what?

Answer 9

Seen with

• BPH
• bladder cancer
• renal cancer

Not seen with early prostate cancer.

Question 10

What is Plaquenil (hydroxychloroquine); what is it used to treat and are there any precautions with its use?

Answer 10

Hydroxychloroquine is used to treat malaria and RA. It can cause retinopathy, so you should always obtain an eye exam at baseline and every 3 months with prolonged use. You should also obtain a CBC is it is used long term

Question 11

Multiple myeloma is a malignancy of…?

Answer 11

The plasma cells.

Question 12

What is a better choice for a sleeping agent for the elderly? Why?

Answer 12

Zolpidem (Ambiem) because of its short half-life.