General Flashcards
1
Q
AI disease on immunosuppression
- general issues for mgmt
A
IMMUNOSUPPRESS BALNCE (control dis/prevent organ damage v S/E)
1. Ax disease activity regularly
- SLE: ?skin, jt, cytopenias; bloods - C3/C4, dsDNA; urine (nephritis)
2. Monitor for drug toxicity
- HCQ retinopathy (baseline then @5y + annual after), OP, bloods
3. CV RF modification
- Control systemic inflammation +/- minimise steroids
- Esp in RA/SLE
4. Cancer screen
- From dis risk + drug risk
- Annual skin, age/gender, dis specific (DM, Scleroderma)
5. Infection: minimise risk
- Vax (not live MMR, VZV, BCG); all inactivated (Pneumovax 5y)
6. Family planning (even from men: Mycophenolate, MTX)
7. Drug specific S/E (IL6 inh w/ lipids + G perf in RA)
