General Flashcards
if a patient has a PE and you give them apixaban what do you need to be aware of
bleed
- GI bleed- ulcer
a patient come in due to SOB
they have myotonic dystrophy
what can be the cause of the SOB
patient has reduced left heart function - reduced ejection fraction due to his heart muscle deteriorating
he also gaimed pneumonina and then also a PE (was sob for 5 weeks then last week got worse- due to the pneumonia and the two PE exaserbatig the SOB)
give furusomide to drain off the fluid round his lungs due to congestion in lungs cus heart failure. give apixaban for the PE. but then this increases fluid for kindeys to deal with and also the fursomide is nephrotoxic the kidneys dont work as well and get heamaturia and bladder distention becasue constipated and blocked.
catheter in for help distended bladder and laxatives.
speak to conusltant - superior- to decide what to do about the bleed injurung the kidneys but then also need anticoag to stop dying from the PE
the decision for this case was stay on apaixaban as need dissolve the clots as the main priority
what is dapagliflozin
treat t2 diabates- if cant have metformin
treat symotomatic heart failure with reduced ejection fraction - good if the pt has renal failure
CKD
works by: Reversibly inhibits sodium-glucose co-transporter 2 (SGLT2) in the renal proximal convoluted tubule to reduce glucose reabsorption and increase urinary glucose excretion
SE: can caues DKA!
if a patient is going to take lots and for longer time of steroids what else do they need to take
PPI = steroids irritate stoamch linigng- inhibit prostaglandins
which drugs have the adverse effect of :
Myelosuppression/agranulocytosis
methotrexate
carbimazole
azathioprine
carbamazepine
phenytoin
which drugs have adverse affects of Lengthens QT interval
antipsychotics
amiodarone
ciprofloxacin
which drugs have adverse effetcs that caue hirtuism
corticosteroids
phenytoin
side effects of cortiocsteroids
hyperlipidameia due to hyperglycemia
medicaions for motion sickness
hyoscine
cyclosine
promethasine
diclofenac is contrainidiacted with what
heart problems/cvd
SE indapamide
gout
thiazide diuretics can cause hyperuricaemia –> gout
SE systemic corticosteroids
altered mood and behaviour
eg. agression
SE prochlorperazine
antipyscootics
extra pyramidal side effects = dystonia
