General Flashcards
Drugs prescribed in micrograms
Levothyroxine Digoxin Colchicine Tamsulosin Inhalers
Drugs to avoid in renal impairment
NSAIDS ACEi ARB Furosemide Spironolactone
Drugs prescribed once weekly
Methotrexate
Alendronate
What drug do you hold when on antibiotics
PPI (risk of C. diff)
What drugs don’t you give in PD
Haloperidol Metoclopramide (domperidone is safe)
When do you check U&E after starting ACEi
2 weeks
What do you monitor when on COCP
BP and Weight at every visit
Main drug co-prescription to avoid in asthma/COPD
Don’t give SAMA and LAMA together
What is INR a measure of in Warfarin therapy
Short term control of coagulation
Common nephrotoxic drugs
Diuretics, especially loop diuretics ACEi/ARBs/mineralocorticoid antagonists NSAIDs Aspirin and paracetamol in overdose Statins and fibrates (with rhabdomyolysis)
Anti-infectives (rarely when oral)
Aminoglycosides such as gentamicin
Vancomycin
Some penicillins and cephalosporins
Intravenous anti-fungals such as amphotericin B
Certain intravenous antivirals such as acyclovir
Radiocontrast agents
Lithium in overdose
Certain immunosupressants and chemotherapy
Diabetes sick day rules
Check blood glucose more often (every 1-2h)
Check blood ketones irrespective of glucose
If appetite reduced can replace meals with carb rich drinks
Drink water/sugar-free fluids if glucose high
Seek medical attention if unable to tolerate oral feeding/fluids due to N+V
Laxative types
Osmotic: Lactulose
Stimulant: Senna
Bulk-forming: Ispaghula husk
Stool softener
Short term constipation (if stools hard)
- Bulk-forming laxative
2. Osmotic laxative
Short term constipation (if stools soft)
Senna
Opioid induced constipation
Osmotic + stimulant laxatives
Faecal impaction Mx
Osmotic laxative e.g. macrogol if hard stool
If soft stool, or stool still hard after macrogol: Add in stimulant laxative
Chronic
N+V in pregnancy
Cyclizine/promethazine (antihistamines)
Prochlorperazine (phenothiazines)
Immediate relief of dyspepsia
Magnesium carbonate antacids
Analgesia regular vs PRN
PRN if intermittent pain
Regular if constant pain
Different statin doses
Lipid lowering = 10mg
Primary CV prevention (e.g. high QRISK) = 20mg
Secondary CV prevention = 80mg
ACEi monitoring for renal function deterioration
○ >20% rise = remeasure renal function within 2 weeks
○ >30% rise = temporary dose reduction or withdrawal
○ >50% rise = Dose reduction or withdrawal
○ >100% rise = stop ACEi and specialist referral
Opioid SEs
N+V
Constipation
Drowsiness
Resp depression
