General 1 Flashcards
level 1 denial
lack of accurate information or internalized wrong information
level 2 denial
consciously defensive/knowledge that something is wrong
level 3 denial
unconsciously defensive/evasion and distortion
level 4 denial
delusional
probability of becoming addicted to cocaine after one use
17%
risk of addiction after one use of methamphetamine
11%
heaving drinking % last 30 days
12%
binge drinking % last 30 days
24.7%
CYP metabolism of methamphetamine
2D6
half life of MDMA
8 hrs
prohibits any agency with federal funds from discrimination
Rehabilitation Act of 1973
enkephalin binds to
delta receptors (G protein coupled)
dynorphins bind to
kappa receptors
half life of cocaine
40-60 min
half life of cotinine
16 hours
past month of users of THC
20 million
twin rate for THC use d/o
28% mono; 9% dizygotic
% who become addicted to nicotine after first try
32%
peak concentration of meth after smoking
2.5 hrs
metabolizes nicontine
CYP2A6
% misusing prescription opioids each year
5%
smoked cocaine lasts…
30 min
intranasal / GI cocaine lasts
2-3 hrs
AA founders
Bill Wilson and Bob Smith - 1935
time since last drink for antabuse
12 hours
% addicted to heroin
23%
% addicted to inhalant drugs
4%
% addicted to alcohol
15%
% addicted to cannabis
9%
Legalization of etoh (law)
Volstead Act - 1919
drug detection time in hair
90 days
CAGE sensitivity and specificity
79%, 77%
most commonly used among adolescents
sedatives and stimulants
AA steps with “God” in them
4
12 month prevalence of prescription OUD
0.9%
lifetime prevalence of prescription OUD
2.1%
main methadone metabolite
EDDP
positive score on AUDIT -C
4 men; 3 women; total 7 indicates AUD
metabolites of disulfiram
carbon disulfide and acetone
positive score on AUDIT
> 8 positive; >20 AUD
most common effect of MDMA
altered perception of time
benzodiazepines metabolized by
CYP3A4
better in AA
male, less psych, more social support to stop drinking
UDS – tests for BZDs that metabolize to
oxazepam
effects of ingested marijuana
6 hours
half life of disulfiram
60-120 hours
methadone metabolite
EDDP
GHB receptor
GABA B
duration of inhaled marijuana
3 hours
salvia binding site
dopamine agonist; kappa opioid agonist
