Gene Regulation (Lac Operon)

Question 1

What is the cost of making a protein?

Answer 1

6,000 ATP for a single copy

Question 2

Many genes are turned on and off as __________________.

Answer 2

the needs of the cell change

Question 3

Gene products that are needed all the time are expressed ____________, as opposed to being regulated.

Answer 3

constitutively

Question 4

Where can gene regulation occur?

Answer 4

1. Transcriptional control
2. Translational control
3. Post-translational control

Question 5

Regulation most frequently occurs at the level of ___________.

Answer 5

Transcription initiation

Question 6

You cannot have β-galactosidase without _________.

Answer 6

lactose

Question 7

Regulation at the transcriptional level ______________.

Answer 7

saves the most energy

Question 8

Regulation at the post-translational level ________________.

Answer 8

takes effect faster

Question 9

Negative control

Answer 9

Occurs when a regulatory protein called a repressor behinds to DNA and shuts down transcription

Question 10

Positive control

Answer 10

Occurs when a regulatory protein called an activator binds to DNA and triggers transcription.

Question 11

Colchicine, colcemid

Answer 11

Binds tubulin monomers, inhibiting assembly

Question 12

Nocadazole

Answer 12

Bind β-tubulin, inhibiting polymerization

Question 13

Vinblastine, vincristine

Answer 13

Aggregates tubulin heterodimers

Question 14

Taxol

Answer 14

Stabilizes microtubules