Gene Regulation

Question 1

How do are different cell types produced

Answer 1

Question 2

How close together are the promoter and enhancer

Answer 2

Question 3

How is the promoter and enhancer brought closer together

Answer 3

Enhancer interacts with promoter

Question 4

What are transcription factors

Answer 4

Question 5

Where can transcription factors bind
Why are base letters different sizes

Answer 5

Question 6

What are pioneer factors and what are their two roles

Answer 6

Discovered in 1991

Question 7

How big are eukaryotic genomes

Answer 7

Question 8

How is the genome compacted

Answer 8

Question 9

What is the difference between heterochromatin and euchromatin
How do you go from hetero to eu

Answer 9

Question 10

How do pioneer factors usually work

Answer 10

Question 11

Can all the enhancers interact with all the promoters?

Answer 11

Question 12

What are TADs

Answer 12

Question 13

How are TADs formed

Answer 13

Question 14

What would happen if there’s a mutation in a TAD (example of PAX3 gene)

Answer 14

Question 15

What are the different stages of RNA pol II

Answer 15

Question 16

What is the role of the C terminal domain (CTD) of RNA pol II

Answer 16

Question 17

Why is there proximal pausing of RNA pol II

Answer 17

Question 18

How is RNA pol 2 paused

Answer 18