Gene Product (Onco + TumSup Genes) Flashcards by Robert Hoyt | Brainscape

Q

ALK

A

Receptor Tyrosine Kinase

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Q

BCR-ABL

A

Tyrosine Kinase

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Q

BCL-2

A

Antiapoptotic molecule

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Q

BRAF

A

Ser/Thr kinase

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Q

C-KIT

A

Cytokine Receptor

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Q

C-MYC

A

Transcription Factor

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Q

HER2/Neu

A

Tyrosine Kinase

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Q

JAK2

A

Tyrosine Kinase

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Q

KRAS

A

GTPase

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Q

MYCL1

A

Transcription Factor

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Q

MYCN1

A

Transcription Factor

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Q

RET

A

Tyrosine Kinase

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Q

BRCA1/BRCA2

A

DNA repair

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Q

CDKN2A

A

p16, G1-S phase transition inhibitor

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Q

DCC

A

DCC (Deleted in Colon Cancer)

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Q

DPC

A

DPC (Deleted in Pancreatic Cancer)

Q

DPC4/ SMAD4

A

Menin

Q

NF1

A

Ras GTPase activating protein

Q

NF2

A

Merlin (shwannomin) protein

Q

Rb

A

Inhibits EF2, G1-S phase transition inhibitor

Q

TP53

A

p53, activates p21, G1-S phase transition inhibitor

Q

TSC1

A

Hamartin

Q

TSC2

A

Tuberin

Q

VHL

A

Hypoxia-Inducible Factor 1a