Gene Associated Condition (Onco + TumSup Genes) Flashcards

1
Q

ALK

A

Lung Adenocarcinoma

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2
Q

BCR-ABL

A

CML, ALL

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3
Q

BCL-2

A

Follicular lymphoma, Diffuse Large B-Cell Lymphoma

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4
Q

BRAF

A

Melanoma, Non-Hodge Lymphoma

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5
Q

C-KIT

A

Gastrointestinal Stromal Tumor (GIST)

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6
Q

C-MYC

A

Burkitt Lymphoma

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7
Q

HER2/Neu

A

Breast and Gastric Carcinoma

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8
Q

JAK2

A

Chronic Myeloproliferative Disorders

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9
Q

KRAS

A

Colon Cancer, Lung Cancer, Pancreatic Cancer

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10
Q

MYCL1

A

Lung Tumors

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11
Q

MYCN

A

Neuroblastoma

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12
Q

RET

A

MEN2A/B, Medullary Thyroid Cancer

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13
Q

APC

A

Colorectal Cancer

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14
Q

BRCA1/BRCA2

A

Breast and Ovarian Cancer

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15
Q

CDKN2A

A

Melanoma, Pancreatic Cancer

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16
Q

DCC

A

Colon Cancer

17
Q

DPC4/SMAD4

A

Pancreatic Cancer

18
Q

MEN1

A

MEN1

19
Q

NF1

A

NF1

20
Q

NF2

A

NF2

21
Q

PTEN

A

Breast, Prostate, Endometrial cancer

22
Q

Rb

A

Retinoblastoma, Osteosarcoma

23
Q

TP53

A

Most cancers, Li-Frau

24
Q

TSC1/TSC2

A

Tuberous Sclerosis

25
Q

VHL

A

Von Hippel Lindau, Renal Cell Carcinoma

26
Q

WT1/WT2

A

Wilms Tumor