gene expression & regulation in eukaryotes

Question 1

central dogma of molecular biology

Answer 1

• genetic information flows only in one direction, from DNA, to RNA, to protein, or RNA directly to protein

Question 2

key stages at which gene expression may be regulated

Answer 2

• transcription control regulates when and how often a gene is transcribed during transcription (nucleus)
• RNA processing control occurs when the RNA transcript is processed into an mRNA
• RNA transport control regulates which mRNAs are exported from the nuclei to the cytosol
• RNA localisation control regulates where mRNAs are localised in the cytosol
• protein function and degradation
• mRNA is either degraded or translated by the ribosome to make protein

Question 3

gene expression in prokaryote vs eukaryotes

Answer 3

• gene expression is regulated only in translation for prokaryotes