Gene Expression Flashcards

0
Q

Mutations in lac Operon

I-

A

prevents repressor from binding

recessive) (on all the time

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1
Q

constitutive Mutation

A

prevents binding of repressor to operator

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2
Q

Mutations in lac operon:

Oc

A

prevents repressor from binding

dominant) (on all the time

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3
Q

mutations in lac operon

Is Superrepressor

A

repressor stays bound to operon all the time

dominant) (on all the time

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4
Q

Mutations in lac operon:

Z-

A

Non-functional galactosidase

doesn’t affect expression, only products

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5
Q

Compact DNA (chromatin)

A

Does not allow transcription to happen

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6
Q

Constitutive Expression

A

Continuous transcription
no regulation, always being expressed
products needed in large quantities

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7
Q

CRP

A

cAMP Receptor Protein

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8
Q

CAP

A

catabolic activator protein

helps activate activator protein but need cAMP to activate

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9
Q

trp Operon

A

synthesized amino acid, tryptophan

  • negative repressible control, repressed by presence or tryptophan
  • structural genes encode enzymes of the tryptophan synthesis pathway
  • products synthesis substrate (tyrptophan) tryptophan turns off operon
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