gene and chromosome mutations Flashcards
what is a gene mutation?
a change in the DNA base sequence
what are the three types of mutation?
substitution
deletion
insertion
what is substition?
one base is replaced by another
what is deletion?
one base i removed from the sequence
what is insertion
one base is added to the sequence
why wont all substition reaction lead to a change in the amino acide?
DNA is degenerate
what are deletion and insetions morelikley to change an amino acide?
causes a frame shift
what is a chromosomone mutation?
involve changes to the structure or number of whole chromosomes. Mutations to chromosome number can arise spontaneously through errors in cell division.
what is polyploidy?
This is when organisms have more than two sets of chromosomes, and is mostly seen in plants.
what is non-disjunction?
This occurs when homologous chromosomes fail to separate in meiosis, resulting in gametes with extra or missing chromosomes, and leads to individuals with extra or missing chromosomes in all cells.