Gen Peds CPS Flashcards
What is the Rome III diagnostic criteria for functional constipation?
Criteria must be fulfilled at least once per week for at least 2 months before diagnosis can be made:2 or more of following in a child of at least 4 yo with insufficient criteria for diagnosis of IBS:1. 2 or few defectations in the toilet per week2. At least one episode of fecal incontinence per week3. History of retentive posturing or excessive volitional stool retention4. History of painful or hard bowel movements5. Presence of a large fecal mass in the rectum6. History of large diameter stools that may obstruct the toilet
When are the two periods of time when the developing child is most prone to functional constipation?
- Toilet training2. Start of school
What is a “fleet enema”?-recommended for what age group?-what are side effects? (3)
Sodium biphosphate and sodium phosphate-recommended for children > 2 years only-side effects:1. mechanical trauma to rectal wall2. abdo distention or vomiting3. hyperphosphatemia, hypocalcemia
What is the potential side effect of use of mineral oil for constipation?-in which group is mineral oil contraindicated?
Lipid pneumonia if aspirated-contraindicated in infants because of this reason
What is distinguishing feature and benefit of Peg 3350 over other laxatives?
Does not cause electrolyte imbalance (only absorbed in trace amounts from the GI tract)
What is the dose of PEG for disimpaction and maintenance?
Disimpaction: 1.5 g/kg/day div BID x 3 dMaintenance: 0.4-1 g/kg/day (start high and then decrease as necessary)
What is a common reason for lack of response to stool softening therapy with PEG?
Inadequate dosing! Start high and then decrease as necessary
What is the evidence for docusate in pediatric constipation?
No evidence that docusate is effective!
What behavioural modification recommendations can be made to parents for treatment of constipation? (3)
- Routine scheduled toilet sitting x 3-10 min once or twice a day2. Footstool to help increase intraabdominal pressure3. No punishment for not stooling during toileting time; yes praise and reward for stooling and toilet sitting
What is the recommended fibre intake for all children?-what is the evidence for fibre supplementation in children with constipation?
0.5 g/kg/day to max of 35 g/day-no evidence to support fibre supplementation
What is the next step if a child is unresponsive to adequate medical and behavioural management for constipation?
Consider time-limited trial of a cow’s milk free diet = CMPI has been associated with chronic constipation
What is considered “normal” for stooling patterns in infants?
Remember that normal breastfed newborns may stool with each feeding or may not stool at all for 7-10 d
How long should children with constipation be treated for with stool softener therapy?
At least 6 months-should have regular BMs without difficulty before considering a trial of weaning maintenance therapy
What is the definition of fever or unknown origin?
Fever > 14 days with no etiology found after routine tests
What are the limitations of a rectal temperature? (5)
- Can be slow to change in relation to changing core temp2. Accuracy depends on depth of measurement3. May be inaccurate if there is decreased local blood flow or stool presence4. Risk for rectal perforation (1 in 2 million)o 5. Can spread infection
What is the AAP recommendation on route of temp measurement as screen for fever in neonates? And why?
Ax temp due to risk of rectal perforation with rectal temps (even though risk is super low)-only used as a SCREEN since it has low sensitivity and specificity in detecting fever
What are the limitations of PO temp? (2)
- Easily influenced by recent ingestion of food or drink and mouth breathing2. Relies on mouth being sealed and tongue being pressed down which is hard for young children or unconscious/uncooperative patients
What is the science behind tympanic thermometers?
Measure thermal radiation emitted from TM and ear canal (infrared radiation emission detectors)-amount of thermal radiation emitted is in proportion to membrane’s temperature and blood supply to this is very similar in temp and location to the blood bathing the hypothalamus which is the body’s thermoregulatory centre-not affected by crying, otitis media or earwax
According to the CPS statement on temperature measurement, what are the normal temperature ranges for:-rectal-ear-oral-axillary
Rectal: 36.6-38Ear: 35.8 - 38Oral: 35.5 - 37.5Ax 34.7 - 37.3
What are the limitations to tympanic temperature?
- Influenced by ear canal’s structure, meatus size and probe positioning (need an adequate seal to protect from ambient temperatures); especially difficult in young children
What is the recommendation for temporal artery thermometry?
May be a useful tool for screening children at low risk in ER but cannot yet be recommended for home use or hospital use when definitive measurements are needed
Overall, what is the recommendation on use of infrared tympanic thermometers?
Accurate, easy and safe to use and so it is an appropriate way to measure temps especially in older children-children < 2 yo should still have temp taken rectally until a better tympanic temp probe is designed
What is the recommended temperature measurement techniques for the following age groups:-birth to 2 yrs-5 yo
-birth to 2 yr: ax as screen rectal as definitive-2-5 yo: ax or tympanic as screen, rectal as definitive-5 yo: ax, tympanic (or temporal artery if in hospital) as screen, oral as definitive
What is the difference between bedsharing and cosleeping?
-Bedsharing: baby shares same sleeping surface with another person-Co-sleeping: baby is within arm’s reach of another person but not on the same sleeping surface
Before 18 months, how fast do children’s feet grow?-what about toddlers?
-<18 mo: Half a shoe size q2months-toddlers: half a shoe size q3months
When does longitudinal arch development occur in children?-what is flexible flatfoot?
Longitudinal arch development occurs before the age of 6-all children < 18 mo have flat feet because of a fat pad under the foot-flexible flatfoot: common in children < 6 yo (developmental variation and normal!!!) and does NOT need treatment (ie. corrective shoes, inserts, etc.) if asymptomatic!
What 3 characteristics of children lead to higher incidence of flatfoot?
- Greater laxity of ligaments2. Obesity3. Shoe wearing in early childhood
What is the treatment and prognosis of intoeing, torsions, knock knees and bowlegs?-when should you consider referral to orthopedic surgeon?
Treatment: NOTHING. Orthotics are NOT beneficial in management of these things! Majority of torsional deformities resolve spontaneously by adulthood and rarely cause functional problems-refer to ortho if persists beyond age ~8 and if it causes functional impairment-corrective shoes or other interventions are NOT necessary if asymptomatic
A mom brings in her 6 month old baby and asks you “Does she need shoes?” What do you answer?
NO! Infants do not need shoes until they are walking-they are necessary for protection and that’s pretty much it.
What questions should you ask when helping parents choose internet sites for high-quality health information? (4)
- Is the host of the health info web site engaged in a conflict of interest?2. Is the info peer reviewed?3. Is the info up to date?4. Is the info presented based on proper evidence?
What type of hearing loss is the most common in neonates?
Sensorineural-genetic cause is found in 50%-of these, 70% have nonsyndromic deafness related to cochlear hair cell dysfunction (errors in production of protein connexin 26)
What is the hearing threshold for normal hearing in decibels?-mild hearing impairment?-moderate?-severe?-profound?
Normal: 0-20 dBMild: 20-40 Moderate: 40-60Severe: 60-80Profound: > 80
What are risk factors for neonatal sensorineural hearing loss? (5)-in what percentage of neonates with hearing loss can a risk factor be identified?
- Family history of permanent hearing loss2. Craniofacial abnormalities including those involving the inner ear3. Congenital infections (bacterial meningitis, TORCH)4. Physical findings consistent with an underlying syndrome associated with hearing loss5. NICU stay > 2 days OR any of the following regardless of duration of stay:-ecmo-mechanical ventilation-ototoxic drug use-hyperbilirubinemia requiring exchange transfusion***Only about 50% of neonates found to have sensorineural hearing loss had an identifiable risk factor. The other 50% had no risk factors at all; this is why universal screening is so important!
What is the average age of diagnosis of hearing loss in unscreened children?-what about screened children?
24 months when there is an expressive language deficit-mild and moderate hearing losses aren’t usually detected until school age-In screened children, average age of diagnosis is 3 months of age with intervention by 6 mo
What are the components of a successful screening test?
- Test is reliable and accurate2. Test can lead to earlier diagnosis3. Little adverse effects of test4. Earlier detection has available and effective intervention5. Good long term outcome from earlier intervention
What are the two screening tests for hearing loss?-main similarities and differences?
***Both tests should be performed in infants > 24 hrs old and > 34 wks CGA-noninvasive1. Otoacoustic emission (OAE)-identifies conductive and cochlear hearing loss from level of external ear to the level of the outer hair cells in the cochlea-sound stimulus is sent to the auditory system via ear specific probes and then echoes returning from the outer hair cells of the cochlea are measured2. Automated auditory brainstem response (AABR)-identifes conductive, cochlear AND NEURAL hearing loss from the external ear to the level of the brainstem including assessment of 8th nerve function-records brainstem electrical activity in response to sounds presented to the infant via earphones
In a newborn with no risk factors for hearing loss, what is the indicated screening test for hearing loss?-in a child with risk factors for sensorineural hearing loss?-in a child who fails the 1st screening test?
2 step screen for infants with no risk factors: use OAE –> if fails –> move onto AABR-in child with risk factors for sensorineural hearing loss: start with AABR
What are cochlear implants?-what are current recommendations for their use?-what are children with cochlear implants at increased risk for getting?
Electronic devices surgically placed in the cochlea to provide stimulation to the auditory nerve = has been shown to be highly effective in hearing and language development-current recommendations: bilateral implantation for children who quality between 8-12 months ofa ge coupled with speech language therapy-increased risk of meningitis
What is the false positive rate for hearing screening tests?
2-4%
What is the management of a child with confirmed hearing loss on screening and diagnostic testing?
- Full hx and pe to rule out associated comorbidities or syndromes2. Consult ENT, ophtho, and genetics-need to confirm vision assessment to maximize sensory input3. CONSIDER neuroimaging studies, renal and cardiac evaluation based on findings
What is ankyloglossia?-what is the association with lactation problems, speech disorders or other oral motor disorders?-is there a way to classify or diagnose ankyloglossia?
Abnormally short lingual frenulum = may result in varying degrees of decreased tongue mobility-inconsistent association with problems!!!-there is no universally accepted definition or criteria for diagnosing ankyloglossia!
What is the recommended management for ankyloglossia?-indication for frenotomy?
Conservative! = no intervention required usually beyond parental education and reassurance-most babies with ankyloglossia don’t have significant consequences and most are able to breastfeed successfully-indication for frenotomy: when complete fusion of the tongue is found (complete ankyloglossia)
What are the complications of frenotomy?
- Bleeding2. Infection3. Injury to Wharton’s duct4. Postoperative scarring resulting in worsened limitation of tongue movement
What is the mechanism of maintaining the circadian rhythm of the sleep-wake cycle?
Secretion of melatonin by the pineal gland in response to darkness
What are the two most common type of sleep disorders in the pediatric age group?
- Delayed sleep phase type-initiation of sleep significantly later than the desired bedtime-sleep latency (time it takes between laying down to sleep and onset of sleep) takes longer than normal 30 minutes2. Behavioural insomnia of childhood-sleep onset association type (caregivers need to do certain things before the child goes or returns to sleep at night)-limit setting type (child stalls or refuses to go to bed or return to bed and the caregiver demonstrates unsuccessful limit-setting behaviours)
What are common medical conditions that can result in insomnia? (3)
- Sleep apnea2. Anxiety3. Depression
What are components of good sleep hygiene? (8)
- Consistent routine = stable bedtime and morning wake time2. Age-appropriate number of hours in bed3. Dark and quiet sleep space4. Avoiding hunger and eating prior to bedtime5. Relaxation techniques before bed6. Avoid caffeine, alcohol and nicotine7. Avoid tv, computers, video games8. Encourage reading prior to bedtime
In what age group can melatonin be used for treatment of insomnia?
Greater than 2 years old (no evidence to support use in children < 2 yo)
What is the 1st line treatment for delayed sleep phase type insomnia?-what about sleep-onset association type?-what is the 2nd line treatment?
***For both, SLEEP HYGIENE INTERVENTION IS 1st LINE! If this fails: then consider pharmacological therapy-Delayed sleep phase type: potential for melatonin to advance onset of sleep is high!-typical dose: 2.5-3 mg in children and 5-10 mg in adolescents 30-60 mins prior to desired bedtime-sleep-onset association type: supported by RCT showing improved sleep onset and sleep duration-same dose as above
What special populations might melatonin be effective in? (4)
- ADHD2. ASD3. Intractable epilepsy4. Neurodevelopmental disabilities
What are the clinical features of plagiocephaly?-what is the expected course of positional plagiocephaly?
- Unilateral flattening of the occiput2. Ipsilateral anterior shifting of the ear-expected course: incidence starts at 6 wks, increases to max at 4 months, then slowly decreases over 2 years with resolution of most cases
What are the risk factors for positional plagiocephaly? (7)
- Male sex2. First born3. Limited passive neck rotation at birth (congenital torticollis)4. Supine sleeping position5. Exclusive bottle feeding6. Tummy time < 3 times per day7. Lower activity level with slower achievement of milestones8. Positional preference of sleeping with the head to same side
What condition is on the differential for positional plagiocephaly?-how can you differentiate on exam between the two?
Craniosynostosis = lambdoid suture involvement is the only craniosynostosis that causes occipital flattening and is very infrqeuent-will generally feel ridging of the affected suture with posterior displacement of the ear (as opposed to anterior displacement with PP)
How do you diagnose positional plagiocephaly?
Clinical diagnosis = only get skull xrays if there is clinical suspicion of craniosynostosis or worsening of head shape at an age when PP would be expected to improve
What are the ways to prevent plagiocephaly? (2)
- Sleep placement: positioning the baby with his/her head to the foot or to the head of the bed on alternating days encouraging the baby to lie on the side of the head that allows them to look into the room2. Tummy time = awake time spent in prone position for at least TID x 10-15 minutes-this also aids in progress of developmental milestones that require prone position
What is the treatment for positional plagiocephaly?-what about helmet therapy?-side effects of helmet therapy?-what is the maximum age to consider helmet therapy?
Overall, for children < 4 months of age with mild-moderate assymmetry: physiotherapy program combining positioning with exercises where needed (congenital torticollis, positional preference or developmental stimulation) is superior to parental counselling for preventive measures without PT supportHelmet therapy: EXPENSIVE with lots of side effects thus is NOT recommended-have to wear 23 hrs/day, associated with contact dermatitis, pressure sores and local skin irritation-can consider in children in severe asymmetry regardless of age-maximum age to try helmet therapy is 8 months*these recommendations are not supported by evidence!
What 3 conditions should be ruled out in children with plagiocephaly?
- Craniosynostosis2. Congenital torticollis3. Cervical spine abnormalities
What is a macrobiotic diet?
Not necessarily vegetarian but is based largely on grains, legumes and vegetables, may contain some animal products
What is the recommended protein intake for vegetarian children compared with nonvegetarians?-what are major plant food sources of protein?
Due to lower digestability of plant proteins, need to increase protein intake for vegetarian children:-< 2 yo: increase by 35%-2-6 yo: increase by 30%-> 6 yo: increase by 20%***Major plant food sources of protein:-legumes (beans and lentils), cereals, nuts and seeds, nut butters-each has different qualities and essential amino acids thus need a mixture of these to have good nutrition
What is the most common nutritional deficiency in children?
Iron deficiency
What is the recommended iron intake for vegetarian vs. non vegetarian children?-sources of iron in plant foods?
Vegetarians require 1.8x the iron intake of nonvegetarians because of different bioavailability-sources of iron: iron-fortified cereals, grain products, dried beans and peas, supplementation
Is zinc supplementation recommended for vegetarian children?
No since zinc deficiency is quite rare-just recommend including zinc rich foods such as legumes, nuts, fermented soy products
In vegetarian children, which subgroup is most likely to be calcium deficient?-calcium rich foods?
Strictly vegan children are at highest risk for calcium deficiency-calcium rich foods: bok choy, chinese cabbage, kale, collards, cereals, juices, soy products -strictly vegan children/adolescents require additional supplementation to ensure recommended intakes
Is calcium content of breast milk affected by a vegan diet in the mother?
No it does not :)-however, after weaning of breastfeeding, should ensure baby gets adequate intake of calcium fortified foods such as fortified soy products, cereals, juices, leafy vegetables
What fat/fatty acids are deficient in a vegan diet?-what are the recommendations in making sure they get enough?
Deficiency in long-chain omega-3-fatty acids (DHA and EPA) = found in fish, seafood and eggs-vegans thus don’t get this unless they eat sea vegetables or algae-recommendations: need adequate sources of the precursor linolenic acid (flaxseed, canola oils, walnuts and soy products) which are then converted into EPA and DHA-can also get microsupplements of microalgae
What vitamin deficiency is often seen in vegans and can have serious neurological consequences?-recommendations for intake?
- Vitamin B12: only found in animal products (meat, eggs. etc)-recommendations: need supplementation or fortified foods for all strict vegan infants/children/adolescents-at least 3 servings of food rich in vitamin B12 in daily diet = fortified soy/nut beverages, cereals OR 5-10 mcg per day-keep in mind that vegetarian diets are usually high in folic acid intake and can therefore mask vit B12 deficiency anemia but children will still have neurological deficits from the vit B12 that can go undetected until too late
What are recommendations for vitamin D intake?-children < 1 yo?-children < 2 yo living above northern lattitude of 55 degrees, dark skin, or avoiding sunlight? Timing?-children > 1 yo
-Children < 1 yo: 400 U vit D OD-Children < 2 yo living above northern lattitude of 55 degrees/dark skin/avoiding sunlight: 800 IU Vit D in winter months from October to April-children > 1 yo otherwise: 200 U vit D OD (sunlight exposure x 20-30 minutes three times per week)
What is the recommended maximum fibre intake?-why do we set a max?
0.5 g/kg/d-set a max so that calories aren’t diluted and there is no interference with absorption of minerals and essential nutrients
How do the birth weights of infants of vegetarian mothers compare with those of nonvegetarians?-what 2 vitamin deficiencies are of concern for infants of breastfeeding vegan mothers?
They are comparable!-vitamin deficiencies:1. Vit B122. Vit D-require adequate sources of both through fortified foods or supplementation during pregnancy and lactation
What is the recommended intake of vitamin D for all pregnant/lactating mothers during the winter months?
2000 U vit D OD
What is the likelihood that a lacto-ovo-vegetarian diet will meet nutrient needs for a growing child?-what about strict vegan diet?
Lacto-ovo-vegetarian diets are adequate to meet all nutrient needs!-strict vegan diet CAN meet the nutrient needs as long as there is intake of calorie-dense foods to provide for adequate growth so should monitor very closely
What are the specific recommendations for strictly vegan children in terms of: (don’t need specific numbers, just increase/decrease/keep same)-protein intake-iron intake-zinc intake for breastfed infants of vegan moms-zinc intake for strict vegans-calcium intake-fatty acid intake-vitamin B12 intake
-protein requirements: need to increase to account for lower digestibility of plant protein-iron needs: need to increase iron fortified foods or supplementation-zinc intake for breastfeeding babies of vegan moms: need fortified foods after 7 months of age-zinc intake for strict vegans: need 50% more daily zinc -calcium intake: need to increase-fatty acid: need to take linolenic acid foods (flaxseed, canola oil, walnuts)-vitamin B12: need to have 5-10 mcg per day
What are the 5 key domains of a child’s early development?
- Physical2. Social3. Emotional4. Language/cognitive5. Communication skills
What is an EDI? :)
Early development instrument: population-based survey that kindergarten teachers fill out across the country to measure child development across the country
What criteria need to be met before a diagnosis of primary nocturnal enuresis can be made? (3)
- Bladder control has never been attained2. Child must be > 5 yo3. Regular bed-wetting (more than twice per week)***Remember that this is a variation in the development of normal bladder control and may be associated with deep sleep patterns
What percentage of 5 yo children still have bedwetting?-8 yo?-15 yo?
5 yo: 10-15%-8 yo: 6-8%-15 yo: 1-2%
Where is the gene for enuresis?
Chromosome 13q
Should you order a urinalysis in a child with primary nocturnal enuresis with normal history and physical exam?
NO! Low pretest probability of a true positive result on UA with potential of getting a false positive result!-thus only order if history or physical suggests to do so
How does an alarm device work in the management of nocturnal enuresis?-what does success of the alarm depend on?-in what age group is the alarm system most effective?
Teaches the child to respond to a full bladder when asleep -goes off when the child starts to void and teaches the child to wake up to the alarm and then transfer the waking to the sensation of a full bladder-worn on the body and runs on miniature batteries, sensitive to a few drops of urine-success depends on the motivation of the child and parent to be awakened-most effective in 7-8 yo
How long should the alarm device be trialed for nocturnal enuresis? -how long does it take to see an improvement?-when can you stop the alarm system if it is successful?-what is the “overlearning” method?
Need to trial the alarm system for 3-4 months as it may take up to 1-2 months to start seeing an improvement-initially, will see decrease in UO as opposed to totally dry night-can stop when there has been 14 consecutive dry nights-some people recommend “overlearning” which is when you reach 14 consecutive dry nights, then the child drinks extra fluid (2 glasses of water) before bed and do this until the patient has achieved 7 dry nights in a row, then can stop the alarm
What is the actual cure rate of primary nocturnal enuresis using alarm devices based on systematic overviews?
Just under 50% but this is still better than nothing so CPS recommends using it!
What are potential side effects of DDAVP for treatment of nocturnal enuresis?
- Headache2. Abdo pain**For intranasal prep:1. Congestion2. Epistaxis
You have prescribed DDAVP to a child with nocturnal enuresis. Mom asks you when he should avoid consuming fluids in relation to when he takes the medication. What is your advice?
No fluids for one hour before and 8 hours after taking desmopressin
What are the options for treating primary nocturnal enuresis? (4)
- Alarm system2. DDAVP (short-term)3. Imipramine4. Behavioural therapy
What is the evidence for use of imipramine in nocturnal enuresis?-dose?
Should only be used as 3rd line (after alarm system and DDAVP) given the possibility of accidental or deliverate overdoseMode of action is unclear but has immediate antienuretic response-recommended dose is 25 mg for children 6-12 yo and 50 mg for > 12 yo-give 1-2 hr before bedtime x 2 wk trial before adjusting dose. Can increase gradually to max of 50 mg-pretty effective, similar to DDAVP but relapse rate is high after stopping, similar to DDAVP
What are possible side effects of imipramine as treatment for primary nocturnal enuresis?
Personality changes, disturbed sleep patterns, headaches, changes in appetite, cardiac arrhythmias, seizures in overdose situations**overall, remember that it’s a TCA!!!!
What is the evidence for behavioural therapy (ie. reward systems) for nocturnal enuresis?
They’re shitty! Don’t do it! How can you convince a child that bedwetting is nothing to be ashamed of if you give them a gold star for not doing it? -decreases self-esteem, increases family conflict and emotional problems
A mom presents with her 7 yo son who has primary nocturnal enuresis. She is very distressed about this and constantly brings up the fact that all the other kids his age have learnt how to not wet the bed. What is your advice?
- Assure mom that this is a normal variation of development and that 6-8% of children his age still have primary nocturnal enuresis.2. Assure child’s access to the toilet3. Avoid caffeine-containing foods and excessive fluids before bedtime4. Have the child empty the bladder at bedtime5. Preserve the child’s self esteem6. Include the child in morning cleanup in a nonpunitive manner7. If this is not distressing for the child, you don’t have to treat!! If it is distressing, then treat.**Your primary goal should be to minimize the emotional impact on the child
What is the most effective therapy for primary nocturnal enuresis?
Conditioning alarm system but only successful in long term in <50% of children
What are individuals with ADHD at increased risk of in their future?
- Reduced quality of life2. Increased risk for injuries3. Behaviour problems4. Difficulty in school (academically and socially)
True or false: treatment with stimulant medication in ADHD is associated with a reduced risk of poor social outcomes, such as developing drug or alcohol addiction.
True!