GBS Flashcards

1
Q
A

Rapid onset
Bilateral
Ascending weakness

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2
Q

Most common infectious cause, and other causes

A

Campylobacter

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3
Q

Is GBS UMN or LMN

A

LMN problem

Hyporeflexia
Reduced power
Reduced tone

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4
Q

What key investigation do you need to do?

A

Spirometry - lung function tests

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5
Q

Anterior horn cell pathology

A

Polio
ALMS
West nile virus

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6
Q

NMJ

A

Myasthenia gravis - anti-acetylcholine receptor
botulinum toxin - honey, tinned foods
Lambert- eaton syndrome

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7
Q

What is lambert eaton syndrome

A

improves with time

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8
Q

When do you get LES

A

Paraneoplastic syndrome - alongside small cell lung cancer

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9
Q

Myopathies

A
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10
Q
A

Voltage gated sodium channels

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11
Q

Management of

A

Steroids may delay recovery

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12
Q

Management of GBS

A

IVIG

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13
Q

How do you get GBS

A

Molecular mimicry of an infection

The lipopolysaccharide in bacteria can mimic the antigen structure of myelin, however not everyone gets it as everyone mounts a different antibody to the bacteria

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