Gastrointestinal Stromal Tumor (GIST) Flashcards by Devon Stutzman | Brainscape

Q

What are Gastrointestinal Stromal Tumors (GISTs)?

A

tumors of connective tissue (sarcomas) unlike most gastrointestinal tumors
they are nonepithelial
70% occur in the stomach, 20% in the small intestine

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Q

How may GISTs present?

A

trouble swallowing, gastrointestinal bleeding, or metastases (mainly in the liver).

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Q

With what genetic mutation are GISTs associated?

A

c-KIT, staining positive for CD 117

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Q

What is the most common mesenchymal neoplasm of the gastrointestinal tract?

A

GIST

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