Gastrointestinal Physiology

Question 1

Identify the trigger, source, and action.

gastrin

Answer 1

T: proteins and amino acids (F, W, M)
S: G cells of the antrum
A: stimulates parietal cells in the fundus for HCl secretion and growth of gastric mucosa

Question 2

Identify the trigger, source, and action.

cholecystokinin

Answer 2

T: all types of food (mainly fats)
S: I cells of the antrum
A: bile secretion, decreases gastric emptying, increases pancreatic enzyme secretion

Question 3

Identify the trigger, source, and action.

secretin

Answer 3

T: H+ in the duodenum, fatty acid in the duodenum
S: S cells of the duodenum
A: inhibits HCl secretion, increases biliary and pancreatic HCO3 secretion

Question 4

Identify the trigger, source, and action.

glucose-dependent insulinotropic peptide (GIP)

Answer 4

T: oral glucose
S: K cells of the duodenum
A: stimulates insulin secretion, inhibits gastric emptying

Question 5

Identify the trigger, source, and action.

motilin

Answer 5

T: fasting
S: M cells of the duodenum
A: activates interdigestive / migrating myoelectric complex

Question 6

Enumerate 5 common drugs that causes gynecomastia

Answer 6

spironolactone
digoxin / digitalis
cimetidine
alcohol
ketoconazole

Some Drugs Create Awesome Knockers